Clinicopathological Factors Affecting Breast Cancer Survival in Jamaican Women: A Retrospective Review

Peters, Kemba A.; Roberts, Patrick; Cornwall, Derria; Mitchell, D. I. G.; Thompson, Rory

doi:10.1007/s40615-022-01273-y

Cited by 2 publications

(1 citation statement)

References 42 publications

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“…In Jamaica, breast cancer accounts for the highest cancerrelated morbidity and mortality in women. This is partly due to the high rates of triple negative molecular subtypes within our population, which is more commonly associated with early treatment failures and overall worse prognosis [16][17][18][19]. Triple negative breast cancers are however associated with high rates of pCR when sequenced with NACT [20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Technetium-99-Guided Axillary Lymph Node Identification: A Case Report of a Novel Technique for Targeted Lymph Node Excision Biopsy for Node Positive Breast Cancer After Neoadjuvant Chemotherapy

Copeland,

Cherian,

Lyew

2023

J Med Cases

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Targeted axillary lymph node identification for breast cancer involves localization and removal of previously marked metastatic lymph nodes after the completion of neoadjuvant chemotherapy (NACT), when clinical and radiological complete responses of the axillary nodes are achieved. Traditionally, axillary lymph node dissection is performed for patients with node positive disease, but the high rates of pathological complete responses now seen after NACT have ushered in lower morbidity techniques such as sentinel lymph node excision biopsies, targeted axillary lymph node dissection and targeted axillary lymph node identification (clip node identification) in node positive disease which has converted to clinical/radiologically node negative. The latter two techniques often require the use of expensive seeds and advanced localization techniques. Here we describe the case of a 59-year-old woman who was diagnosed with node positive invasive breast cancer who was sequenced with NACT. We developed a novel technique, where technetium-99m was injected directly into a previously clipped metastatic axillary lymph node which was then localized with the Neoprobe gamma detection system intra-operatively and removed. This is a relatively low-cost technique that can be easily introduced in limited resourced health systems where radio-guided sentinel lymph node biopsies are already being performed.

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