Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma

Liu, Xiaodie; Zhang, Xue; Pang, Yingxin; Ma, Yonggang; Zhang, Xiaolei; Liu, Peishu

doi:10.1007/s00404-020-05502-9

Cited by 21 publications

(75 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results are in accord with those reported in textbooks of pathology and other publications on rare malignant germ cell tumors, in that most tumors were diagnosed in young patients, all were unilateral and most were large and purely solid 12–14,28 . In our study, three patients (23.1%) were postmenopausal.…”

Section: Discussionsupporting

confidence: 93%

“…In our study, three patients (23.1%) were postmenopausal. Liu et al 13 found, by reviewing the literature, that 6/39 (15.4%) patients with non-gestational choriocarcinoma were postmenopausal, whereas the peak incidence was in the lower age range of 12-25 years. Acute abdomen resulting from torsion, tumor rupture or hemoperitoneum, described in rare cases in the literature 22 , was not observed in our study.…”

Section: Discussionmentioning

confidence: 99%

“…Non‐gestational ovarian choriocarcinoma typically affects children and young adults, and may occasionally be diagnosed in postmenopausal women 10–12 . Non‐gestational choriocarcinomas have a poorer prognosis than do gestational choriocarcinomas 13 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non‐gestational choriocarcinomas and malignant mixed germ cell tumors

Moro

Castellano

Franchi

et al. 2021

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

What are the novel findings of this work?Ultrasound characteristics of rare germ cell tumors are poorly described. The present study describes the clinical and ultrasound characteristics of three types of rare malignant ovarian germ cell tumor: embryonal carcinoma, non-gestational choriocarcinoma and malignant mixed germ cell tumor. What are the clinical implications of this work?Knowledge of the clinical and ultrasound features of germ cell tumors helps clinicians identify or suspect these neoplasms. The ultrasound patterns of embryonal carcinomas, non-gestational choriocarcinomas and malignant mixed germ cell tumors differ from those of epithelial ovarian cancers and other germ cell tumors.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non‐gestational choriocarcinomas and malignant mixed germ cell tumors

Moro

Castellano

Franchi

et al. 2021

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

“…Based on symptoms, physical examinations, imaging examinations on testes and serum tumor markers, all suspicious patients are recommended to have radical inguinal orchiectomy or inguinal exploration (2). Liu et al analyzed various factors for prognosis in non-gestational ovarian choriocarcinoma patients and found that ovariectomy is a good prognostic factor for OS (17). Once choriocarcinoma is confirmed, subsequent treatment regimens such as: retroperitoneal lymph node dissection (RPLND), chemotherapy and surveillance are employed individually or in combination according to TMN stage, S stage and clinical risk factors.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological characteristics and survival outcomes for testicular choriocarcinoma: a population-based study

Cai

Liu

et al. 2021

Transl Androl Urol

View full text Add to dashboard Cite

Background: Due to the scarcity of cases of testicular choriocarcinoma (CC), its clinicopathological characteristics and prognosis have not been well summarized. Consequently, we conducted this populationbased case-control study to characterize the features of testicular CC. Methods:The SEER database was used to extract qualified data. Dichotomous variables were compared by Pearson's Chi-squared or Fisher exact test. Survival variables were compared by Kaplan-Meier analyses and log-rank tests. The univariable and multivariable Cox regression analyses were applied to figure out risk factors for overall survival (OS) and cancer-specific survival (CSS). Propensity score matching (PSM) was used to control confounding factors in the study.Results: In total, 788 patients with CC and 19,571 patients with seminoma were identified. Significant differences were found between two groups in terms of age (≤30 years: 65.4% vs.

show abstract

“…Además, suele el tumor anexial suele manifestarse como una necrosis hemorrágica; y microscópicamente está constituido por sincitotrofoblasto y citotrofoblasto. En recientes investigaciones publicadas, se tienen datos sobre algunos de los factores pronósticos para orientar el tratamiento oncológico individualizado 5 .…”

Section: Introductionunclassified

Coriocarcinoma no gestacional primario de ovario. A propósito de un caso y revisión de la literatura

Gonzales-Medina

Gálvez-Vizcarra

Aguilar-Ramos

et al. 2021

Investigación Materno Perinatal

View full text Add to dashboard Cite

Se presenta el caso clínico de una paciente con diagnóstico de coriocarcinoma primario no gestacional de ovario que corresponde a una neoplasia maligna germinal. Asimismo, se revisa la literatura actualizada del tema haciendo énfasis en la biología molecular, el diagnóstico y el manejo oncológico inicial. Se desarrolló en el Hospital Nacional Dos de Mayo (HNDM) en el servicio de Ginecología Oncológica, Lima, Perú. Se registra el presente caso por su poca casuística en nuestro medio y por el importante valor del criterio oncológico en el manejo de masas anexiales ováricas.

show abstract

Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma

Cited by 21 publications

References 44 publications

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non‐gestational choriocarcinomas and malignant mixed germ cell tumors

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non‐gestational choriocarcinomas and malignant mixed germ cell tumors

Clinicopathological characteristics and survival outcomes for testicular choriocarcinoma: a population-based study

Coriocarcinoma no gestacional primario de ovario. A propósito de un caso y revisión de la literatura

Contact Info

Product

Resources

About