Clinicopathological features and post-resection outcomes of biliary cystadenoma and cystadenocarcinoma of the liver

Jwa, Eunkyoung; Hwang, Shin

doi:10.14701/ahbps.2017.21.3.107

Cited by 19 publications

(25 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A retrospective study conducted by Jwa et al . in South Korea showed that in patients undergoing complete resection there was no tumor recurrence in patients with BCA and in patients with BCAC, 1-, 3- and 5-year disease-free and overall patient survival rates were 100%, 85.7%, 57.1%, and 100%, 100%, 75.0% respectively [ 34 ].…”

Section: Biliary Cystadenocarcinomamentioning

confidence: 99%

An updated review of cystic hepatic lesions

Rawla¹,

Sunkara²,

Muralidharan³

et al. 2019

ceh

View full text Add to dashboard Cite

Cystic hepatic lesions are commonly encountered in daily practice. The diagnosis of these lesions ranges from benign lesions of no clinical significance to malignant and potentially lethal conditions. The prevalence of hepatic cyst (HC) has been reported to be as high as 15-18% in the United States. Imaging with conventional ultrasound, computed tomography, magnetic resonance imaging, or contrast-enhanced ultrasound can be used to characterize further and diagnose. The pre-test probability of a diagnosis is highly affected by the patient’s comorbidities and the clinical and laboratory data; thus, imaging studies should be interpreted in the context of the other clinical information for that particular patient. Treatment modalities for hepatic cyst include fenestration, aspiration sclerotherapy, or surgical resection. In the current review, we discuss the pathophysiology, diagnosis, and treatment modalities for various cystic hepatic lesions.

show abstract

Section: Biliary Cystadenocarcinomamentioning

confidence: 99%

An updated review of cystic hepatic lesions

Rawla¹,

Sunkara²,

Muralidharan³

et al. 2019

ceh

View full text Add to dashboard Cite

show abstract

“…10 The current literature suggests that cystadenocarcinomas have a fairly favorable prognosis if completely resected. 10,11 However, one series suggests that an anaplastic alteration is a sign of impending aggressive invasion by the tumor. 9 In that series, all 3 patients with an anaplastic component died of their disease.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Hepatobiliary Cystadenocarcinoma Mimicking a Gynecologic Malignancy

O’Donnell¹,

Devaraj²,

Post³

2022

AJSP: Reviews and Reports

View full text Add to dashboard Cite

Hepatobiliary cystadenocarcinoma is a rare malignancy associated with ovarian-like stroma and overtly malignant glands that has a favorable prognosis if completely resected, analogous to minimally invasive adenocarcinoma arising in mucinous cystic neoplasms of the pancreas. Ovarian mucinous neoplasms may have a similar histologic appearance and are known to occasionally contain mural nodules of anaplastic carcinoma. We report a case of hepatobiliary cystadenocarcinoma that subsequently presented as metastatic disease mimicking a primary gynecological malignancy. The 30-year-old patient had a history of a completely resected hepatobiliary cystadenocarcinoma 2 years prior to presentation, without adjuvant therapy. She presented to her gynecologist with pelvic pain and vaginal bleeding. Physical examination revealed diffuse nodularity along the anterior vaginal wall, and imaging showed a 5.8 Â 4.1 cm pelvic mass with diffuse metastatic disease. Biopsies of the vaginal wall and an inguinal lymph node showed nests of pleomorphic cells with squamoid and glandular features concerning for metastatic ovarian carcinoma; however, immunohistochemistry was negative for PAX8 and ER, but positive for CDX2. Subsequent review of the patient's prior resection revealed a cystic mucinous neoplasm with mural nodules of adenosquamous and anaplastic carcinoma, the latter previously reported only rarely in hepatobiliary cystadenocarcinoma. This case highlights the histologic overlap between hepatobiliary and ovarian neoplasms, which may present a diagnostic challenge, particularly in the setting of incomplete history. In addition, the unusual presence of an anaplastic component in the patient's original tumor portends a worse prognosis; therefore, additional therapy should be considered in these patients.

show abstract

“…MCN-L has previously been known as biliary cystadenoma or cystadenocarcinoma [ 3 ]. We have previously reported 23 cases of biliary cystadenoma and seven cases of biliary cystadenocarcinoma [ 9 ], for which the definition of MCN-L according to the WHO 2010 classification was not adopted because these study patients had undergone surgical resection between 2007 and 2013.…”

Section: Introductionmentioning

confidence: 99%

Pedunculated mucinous cystic neoplasm of the liver: a case report

Hwang

Han

et al. 2022

J Yeungnam Med Sci

Self Cite

View full text Add to dashboard Cite

In 2010, the World Health Organization classified mucin-producing bile duct tumors of the liver into two distinct entities; mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct. We present the case of a patient with MCN-L having a uniquely pedunculated shape. A 32-year-old woman was referred to our institution with a diagnosis of biliary cystic neoplasm. She had undergone left salpingo-oophorectomy for ovarian cancer 15 years ago. Imaging studies showed an 8 cm-sized well defined, multiloculated cystic lesion suggesting a mucinous cystic neoplasm. The cystic mass was pedunculated at the liver capsule and pathologically diagnosed as MCN-L. The mass was resected with partial hepatectomy. The patient recovered uneventfully. She was discharged 7 days postoperatively. The patient has been doing well for 6 months after the operation. The patient will be followed up annually because of the favorable postresection prognosis of MCN-L.

show abstract

Clinicopathological features and post-resection outcomes of biliary cystadenoma and cystadenocarcinoma of the liver

Cited by 19 publications

References 19 publications

An updated review of cystic hepatic lesions

An updated review of cystic hepatic lesions

Metastatic Hepatobiliary Cystadenocarcinoma Mimicking a Gynecologic Malignancy

Pedunculated mucinous cystic neoplasm of the liver: a case report

Contact Info

Product

Resources

About