Clinicopathological, Microbiological and Polymerase Chain Reaction Study in a Case of Nocardia Scleritis

Agarwal, Mamta; Patnaik, Gazal; Sanghvi, Kaushal; Anand, Appakkudal R.; Janani, M K; Biswas, Jyotirmay

doi:10.1080/09273948.2020.1770299

Cited by 5 publications

(1 citation statement)

References 18 publications

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“…Nocardia asteroides has previously been described to cause scleritis in a patient with leucocytoclastic vasculitis following explantation of an extruded scleral buckle, who was successfully treated with antibiotics 14. A further case report describes a 32-year-old man with tubercular scleritis and Nocardia cyriacigeorgica superinfection, which again responded to topical and oral antibiotics 15. An 11-year retrospective review found that ocular exposure to soil or plant matter was the most common historical points in the development of Nocardia scleritis (45% patients), with most (63.4%) patients with Nocardia scleritis presenting with nodular lesions with pointed abscesses.…”

Section: Discussionmentioning

confidence: 96%

Surgically-induced necrotising scleritis complicated byNocardiainfection following routine cataract surgery

Richardson-May

Chihaia²,

Rashid³

2022

BMJ Case Rep

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Necrotising scleritis is a rare, inflammatory condition with potentially devastating visual consequences. It can be associated with inflammatory and infectious causes, and has been linked to several different ocular procedures. We present a difficult case of a patient with surgically-induced necrotising scleritis following routine phacoemulsification cataract surgery, who developed a secondary Nocardia bacterial infection. He required a number of surgical interventions and prolonged antibiotic therapy, suffering recurrent scleral abscesses. A literature review accompanies our case report. Prompt recognition and adequate investigation for underlying inflammatory and infective causes are vital to maintain integrity of the globe and ensure suitable treatment of this challenging condition.

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Section: Discussionmentioning

confidence: 96%