Clinicopathological Study of Canine Oral Epulides.

Abstract

ABSTRACT. To clarify the clinicopathological features of canine epulides, 189 epulides were reviewed retrospectively. The incidence of the fibromatous, ossifying, acanthomatous and giant cell epulides were 56.6% (107/189), 23.3% (44/189), 18.0% (34/189) and 2.1% (4/189), respectively. The average ages of dogs with fibromatous, ossifying, acanthomatous and giant cell epulides were 8. 8, 8.4, 7.8 and 8.7 years, respectively. The male/female ratio of dogs with the acanthomatous epulis (0.8) was lower than those of dogs with the fibromatous (1.9), ossifying (1.4) and giant cell epulis (3.0). There were slight breed differences among the types of epulides. The most noticeable result was that 38.2% of the acanthomatous epulis occurred in Shetland sheepdogs. 43.9% of the fibromatous epulis and 52% of the ossifying epulides arose around maxillary premolars, while 58.8% of the acanthomatous epulis arose around the mandibular canines. Dogs with the fibromatous and ossifying epulides had more severe dental plaque deposition than those with the acanthomatous epulides. Few of the fibromatous (6/104) or ossifying epulides (4/44) showed recurrence after excision, while the majority (21/23) of the acanthomatous epulides showed rapid and repeated recurrences after surgical excision. Epulides treated with hemimandibulectomy or bleomycin chemotherapy did not recur. Giant cell epulides showed no recurrence after surgical removal. These results indicate that the acanthomatous epulis differed from other types of epulides in biological and morphological features and poor prognosis.-KEY WORDS: canine, clinicopathology, epulis.

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies

“…8,10 International, multicenter studies would be preferable in order to establish which breeds are predisposed to oral neoplasms. This problem is illustrated by the differences in breed distribution between our material and that of other investigators.…”

“…[1][2][3][4][5][6][7][8][9][10] The first survey of both neoplastic and non-neoplastic oropharyngeal lesions in domestic animals reported that 20 % of all canine oral lesions were non-neoplastic, 39 % benign neoplasms, and 41 % malignant neoplasms. [1][2][3][4][5][6][7][8][9][10] The first survey of both neoplastic and non-neoplastic oropharyngeal lesions in domestic animals reported that 20 % of all canine oral lesions were non-neoplastic, 39 % benign neoplasms, and 41 % malignant neoplasms.…”

Clinical and Histologic Features of 26 Canine Peripheral Giant Cell Granulomas (Formerly Giant Cell Epulis)

“…5,8,13,17,18,21,22,25 Although human peripheral giant cell granulomas are generally considered reactive and non-neoplastic, the cause of these lesions is poorly understood. 13,17,18 Six reported cases of canine peripheral giant cell granuloma did not recur after surgical excision.…”

A Clinicopathological Study of 52 Feline Epulides

“…4 Giant cell epulides are both clinically and pathologically less well characterized but exhibit an aggressive clinical course and are, unlike in dogs, reported to recur after surgery. 19,28 Because of the resemblance of the MGCs to foreign body-type giant cells, the giant cell epulis sometimes is considered to represent a reactive giant cell-rich granulomatous lesion, but the real origin remains unknown. 19,21 In human oral cavity proliferations containing MGCs, like the central and peripheral giant cell granuloma, MGCs have been considered as phagocytes, 12 foreign body cells, 24 or osteoclasts.…”