Clomiphene citrate usage pattern in India: A knowledge, attitude, and practice survey among gynecologists

Malik, Sonia; Swami, Onkar C; Prasad, Sudha; Talwar, Pankaj; Verma, Susheel; Jain, Kuldeep; Nayar, Kanad Dev; Devi, G. Gayathiri; Jindal, Umesh

doi:10.4103/2394-4285.162779

Cited by 5 publications

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“…A KAP survey are used to explore the current behaviour of health care practitioners towards specific situation. 7 In present KAP survey, Tenecteplase was the most commonly preferred thrombolytic agents in AIS as the reason behind it may be factors like ease of administration, clinical efficacy and low therapy cost. As mentioned in the literature the cost effectiveness, ease of administration was the factors which influence the use of tenecteplase.…”

Section: Discussionmentioning

confidence: 97%

“…The questionnaire consisted of 18 multiple-choice questions (MCQs), out of which 4 questions were pertaining to knowledge, 6 to attitude and 8 to practice about Tenecteplase usage in routine clinical practice. 7 Knowledge related questions as follows: commonly used diagnostic tool, percentage of patients had successful recanalization after Tenecteplase therapy, percentage of patients who gets tenecteplase as bridging therapy before thrombectomy, frequency of adverse effects noted with Tenecteplase.…”

Section: Methodsmentioning

confidence: 99%

“…These surveys are accepted and commonly used because they apply fewer resources and tend to be more cost-effective than other social research methods and provide useful insights. 7 There are limited data about the knowledge, perception, and routine clinical usage pattern of Tenecteplase among Indian neurologists. The present survey was undertaken to explore knowledge, perception, and usage of Tenecteplase in the real-life setting in India.…”

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confidence: 99%

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Role of Tenecteplase in management of acute ischemic stroke: a knowledge, attitude, and practice survey among Indian neurologists

2021

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Background: Tenecteplase, a third generation tissue plasminogen activator has important place in the thrombolytic therapy in acute ischemic stroke. The objective of present study was to understand the knowledge, attitude and practice (KAP) towards the usage of tenecteplase in daily clinical practice.Methods: This was a prospective questionnaire based knowledge, attitude and practice survey with involvement of practising neurologists across the country. A specially designed validated questionnaire containing 18 questions was shared with neurologists and their anonymous inputs were captured and analysed in qualitative manner.Results: Total Sixty-eight neurologists completed this questionnaire. The 73 percent of neurologist preferred tenecteplase in stroke patients arriving within 4.5 hours of onset of stroke symptoms. Almost 70% of neurologists preferred tenecteplase in patients <60 years of age with average NIHSS score between 5-15. The preferred dosage was 0.2 mg/kg by majority (78%). Bridging therapy was used up to 0-10% of patients by 70% neurologists which ultimately has lesser bleeding chances. 46% neurologists reported that no sICH after tenecteplase, while 30% reported in <1% patients. Almost 70% neurologists reported no allergic reaction noted with tenecteplase. Overall, 70% neurologists reported good to very good improvement in the patient’s quality of life at 90 days after tenecteplase therapy.Conclusions: The current KAP survey emphasized tenecteplase as a commonly preferred thrombolytic agent in acute ischemic stroke with better efficacy and safety, affordable cost with single bolus administration.

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Section: Discussionmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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