“…By using CSA, the current position are optimised in the same search space by maintenance of a memory set, selection and cloning of the most activated antibodies, death of non-activated antibodies, affinity maturation through the mutation process, reselection of clones proportional to the antigen affinity, generation and maintenance of diversity (Jeronymo et al 2010). This leads to an acceleration of the search process and a greater diversity of particles in the search space (Brownlee 2005).…”