1979
DOI: 10.1002/j.1879-3479.1979.tb00479.x
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Clonidine in the Treatment of Menopausal Symptoms

Abstract: Thirty-seven women complaining of hot flushes, sweating and other menopausal symptoms were treated with clonidine. A double-blind crossover trial with placebo controls was undertaken. The clonidine dose was 2 X 0.025 mg/24 hours-0.075 mg/24 hours, increased if necessary at intervals of two weeks. The effect of clonidine did not differ significantly from placebo effect in the treatment of the symptoms. Side effects during clonidine management were slight and no difference was seen in their incidence compared wi… Show more

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Cited by 21 publications
(4 citation statements)
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“…Another study found no difference in hot flashes when clonidine 0.025-0.075 mg twice/day was compared with placebo after 6 weeks of treatment. 32 As with other clonidine trials, a placebo effect was noted.…”
Section: Postmenopausal Hot Flashesmentioning
confidence: 66%
“…Another study found no difference in hot flashes when clonidine 0.025-0.075 mg twice/day was compared with placebo after 6 weeks of treatment. 32 As with other clonidine trials, a placebo effect was noted.…”
Section: Postmenopausal Hot Flashesmentioning
confidence: 66%
“…Clinical trials and reports of prescription drugs studied for treatment of vasomotor symptoms are detailed in Table 1. 9,34…”
Section: Prescription Medicinesmentioning
confidence: 99%
“…Six were identified; 3 found positive results and 3 reported no benefit. 9,14 The largest trial evaluated a broad dose range of clonidine in 86 postmenopausal women with hot flashes. 10 Results showed significant reductions in frequency, severity, and duration of hot flashes in women following 4 weeks of treatment versus placebo (p < 0.05).…”
Section: Prescription Medicinesmentioning
confidence: 99%
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