Clonidine versus tramadol for post spinal shivering during caesarean section: A randomized double blind clinical study

Reddy, Velayudha Sidda; Chiruvella, Sunil

doi:10.4103/2249-4472.84252

Cited by 13 publications

(1 citation statement)

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“…It is associated with multiple side effects including nausea and vomiting which is cause of distress in obstetric population. 16,17 Dexmedetomidine is alpha 2 receptor agonist which is used as antihypertensive, analgesic, sedative and anti-shivering agent. 18,19 Dexmedetomidine can terminate shivering via inhibition of alpha 2 mediated adenyl cyclase in CNS and causing vasoconstriction.…”

Section: Discusssionmentioning

confidence: 99%

Comparison of Intravenous Dexmedetomidine and Tramadol for Management of Post-Spinal Anesthesia Shivering in Obstetric Cases

Talat,

Islam,

Bhatti

et al. 2023

J. Bahria Uni. Med. Dent. Coll.

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Objective: The objective of this study is to compare the efficacy of dexmedetomidine and tramadol in controlling postspinal anesthesia shivering in female patients after cesarean section. Study Design and Setting: Quasi-experimental Study. Anesthesia Department of Combined Military Hospital, Thal from October 2022-March 2023. Methodology: This study was conducted in ASA I and II patients aged 18-45. Sixty patients were enrolled for the study, who were divided into two group, group D received Inj dexmedetomidine (0.5mcg/kg) while group T received Inj Tramadol (0.5mg/kg). Time from injection of drug to cessation of shivering was recorded. End point of study was 30 mins after entry of patient in Post Anesthesia Care Unit (PACU). Results: The study found that both drugs were effective in preventing shivering, but dexmedetomidine had a faster onset of action and a longer duration of action than tramadol. Mean time of cessation of shivering in both groups was calculated. In group D mean time of cessation was 2.9 ±0.9 while in group T it was 3.75 ±0.9. P-value was found to be highly significant 0.001. Conclusion: The study concludes that dexmedetomidine is a more effective and safer alternative to tramadol for management of shivering in patients undergoing lower segment cesarean section under spinal anesthesia.

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Section: Discusssionmentioning

confidence: 99%

Comparison of Intravenous Dexmedetomidine and Tramadol for Management of Post-Spinal Anesthesia Shivering in Obstetric Cases

Talat,

Islam,

Bhatti

et al. 2023

J. Bahria Uni. Med. Dent. Coll.

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Prophylactic vs. therapeutic magnesium sulfate for shivering during spinal anesthesia

Ibrahim

Megalla

Khalifa

et al. 2014

Egyptian Journal of Anaesthesia

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Dexmedetomidine versus Nalbuphine for treatment of postspinal shivering in patients undergoing vaginal hysterectomy: A randomized, double blind, controlled study

Megalla

Mansour

2017

Egyptian Journal of Anaesthesia

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Objectives: Shivering is very distressing for the patient therefore, control of postspinal shivering is essential for proper perioperative care. This study was designed to compare the efficacy, safety and cost effectiveness of Dexmedetomidine and Nalbuphine in the treatment of postspinal shivering. Methods: In this prospective, randomized, double-blind, placebo controlled study, 75 American Society of Anesthesiologists Grade I and II females scheduled for vaginal hysterectomy under spinal anesthesia, who developed shivering grade 3 or 4 were included. The patients were randomized into three groups of 25 patients each to receive either Nalbuphine 0.07 mg/kg (group N) or Dexmedetomidine 0.5 lg/kg (group D) or saline (group C) as a slow intravenous bolus for treatment of shivering. Onset of shivering, grade of shivering, time for cessation, response rate, recurrence, hemodynamic parameters and adverse effects were observed at scheduled intervals. Results: It was observed that the mean response time for control of shivering was significantly less in Group D (1.97 ± 0.61 min) compared to Group N (3.56 ± 0.82 min) and Group C (12.4 ± 3.74 min). Success rate in Group D was 100% compared to 92% in Group N and 32% in Group C. Relapse of shivering was observed more in patients of Group N (8.7%) as compared to Group D (0%) while shivering reappeared in 75% of patients who responded to saline treatment. Among the side effects, sedation was found in both groups N and D. Bradycardia and hypotension were more frequent in Dexmedetomidine group although none of the patients required treatment. Pain during injection was an outstanding complaint in Nalbuphine group. Conclusion: Both Nalbuphine and Dexmedetomidine control shivering effectively, but Dexmedetomidine seems to be a better choice than Nalbuphine for treatment of postspinal shivering due to its shorter response time, lower recurrence rate and associated sedation. Meanwhile, Nalbuphine offers more hemodynamic stability and lower costs.

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Clonidine versus tramadol for post spinal shivering during caesarean section: A randomized double blind clinical study

Cited by 13 publications

References 0 publications

Comparison of Intravenous Dexmedetomidine and Tramadol for Management of Post-Spinal Anesthesia Shivering in Obstetric Cases

Comparison of Intravenous Dexmedetomidine and Tramadol for Management of Post-Spinal Anesthesia Shivering in Obstetric Cases

Prophylactic vs. therapeutic magnesium sulfate for shivering during spinal anesthesia

Dexmedetomidine versus Nalbuphine for treatment of postspinal shivering in patients undergoing vaginal hysterectomy: A randomized, double blind, controlled study

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