1988
DOI: 10.1128/mcb.8.1.160-168.1988
|View full text |Cite
|
Sign up to set email alerts
|

Cloning and Characterization of a cDNA Encoding Transformation-Sensitive Tropomyosin Isoform 3 from Tumorigenic Human Fibroblasts

Abstract: We isolated a cDNA clone from the tumorigenic human fibroblast cell line HuT-14 that contains the entire protein coding region of tropomyosin isoform 3 (Tm3) and 781 base pairs of 5'- and 3'-untranslated sequences. Tm3, despite its apparent smaller molecular weight than Tm1 in two-dimensional gels, has the same peptide length as Tm1 (284 amino acids) and shares 83% homology with Tm1. Tm3 cDNA hybridized to an abundant mRNA of 1.3 kilobases in fetal muscle and cardiac muscle, suggesting that Tm3 is related to a… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

1988
1988
1994
1994

Publication Types

Select...
3

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
references
References 51 publications
0
0
0
Order By: Relevance