Cloning, expression and characterization of a dipteran farnesyl diphosphate synthase

Aphid alarm pheromone: An overview of current knowledge on biosynthesis and functions

“…In insects, farnesyl diphosphate synthases have been most intensively studied because of their implication in the biosynthetic pathway of the sesquiterpenoid juvenile hormone (Castillo-Gracia and Couillaud, 1999;Cusson et al, 2006;Kikuchi et al, 2001;Koyama et al, 1985;Sen and Sperry, 2002;Sen et al, 2007). Recently, a geranylgeranyl diphosphate gene involved in termite defense secretions was also cloned (Hojo et al, 2007).…”

DPP-mediated TGFβ signaling regulates juvenile hormone biosynthesis by activating the expression of juvenile hormone acid methyltransferase

“…Genes associated with these mutations encode proteins with various molecular functions, including enzymes, signal transduction molecules, transcriptional factors and others. Some of them are known to be involved in JH biosynthesis, such as farnesyl diphosphate synthase (FPPS) (Sen et al, 2007) and NMDAR1 (Chiang et al, 2002).…”

Molecular cloning and characterization of a prenyltransferase from the cotton aphid, Aphis gossypii

“…These structural features have been used to identify new prenyltransferases of various sources. The first fulllength cDNA encoding an insect farnesyl diphosphate synthase (FPS) was obtained from the moth Agrotis ipsilon (Castillo-Gracia and Couillaud, 1999), but insect prenyltransferases have been principally studied in recent years (Gilg et al, 2005;Cusson et al, 2006;Kinjoh et al, 2007;Sen et al, 2007aSen et al, , 2007bLewis et al, 2008;Taban et al, 2009), focusing on molecular cloning, structural modeling and functional expression.…”