Cloning of two chemokine receptor homologs (CXC-R4 and CC-R7) in rainbow trout <i>Oncorhynchus mykiss</i>

Daniels, Garry D.; Zou, Jun; Charlemagne, Jacques; Partula, Sylvie; Cunningham, Charles; Secombes, Christopher J.

doi:10.1002/jlb.65.5.684

Cited by 58 publications

(21 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among teleost fishes only one species has previously been reported to possess chemokine (C-C motif) receptor, namely rainbow trout CCR7 (Daniels et al, 1999). In the present study, we confirmed that at least 17 chemokine (C-C motif) receptor genes are present in the zebrafish.…”

Section: Discussionsupporting

confidence: 87%

“…Although C-C chemokine receptors were well studied in mammals, information on the existence of C-C receptors in teleost fish is still rather limited with only a few reports from rainbow trout Oncorhynchus mykiss (Daniels et al, 1999), zebrafish (Danio rerio) and pufferfish (Fugu rubripes) (DeVries et al, 2006). To elucidate this question, all C-C chemokine receptor subfamily members in teleost fish were searched from available database, and their genomic structure and characterization in relation to known C-C chemokine receptor genes in other vertebrate species were reported in this study.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Characterization of C–C chemokine receptor subfamily in teleost fish

Liu

Chang

et al. 2009

Molecular Immunology

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Characterization of C–C chemokine receptor subfamily in teleost fish

Liu

Chang

et al. 2009

Molecular Immunology

View full text Add to dashboard Cite

“…In Table 1, the amino acid identity of the present deduced trout OSU IL-8 receptor protein sequence is compared with other reported carp and mammalian IL-8 receptors (CXCR1 and CXCR2) as well as with the rainbow trout and sterlet CXCR4 [9,11]. Our reported trout IL-8 receptor has high amino acid sequence divergence with teleost CXCR4; however, from the cDNA sequence and deduced amino acid sequence, we can not confirm whether our reported sequence is CXCR1 or CXCR2.…”

Section: H Zhang Et Almentioning

confidence: 99%

Molecular cloning and genomic structure of an interleukin-8 receptor-like gene from homozygous clones of rainbow trout (Oncorhynchus mykiss)

Zhang¹,

Thorgaard²,

Ristow³

2002

Fish & Shellfish Immunology

View full text Add to dashboard Cite

“…Many cytokine genes have also been isolated from different species of bony fish over the last few years. For example, in rainbow trout, two IL-1␤ genes (7,8), three isoforms of TGF-␤ (9 -11), two TNF-␣ genes (12), and several chemokines and their receptors (13,14) have been cloned and sequenced. In cartilaginous fish no cytokine or cytokine receptor genes have been cloned or sequenced to date.…”

mentioning

confidence: 99%

The First Cytokine Sequence Within Cartilaginous Fish: IL-1β in the Small Spotted Catshark (Scyliorhinus canicula)

Bird

Wang

Zou

et al. 2002

The Journal of Immunology

Self Cite

106

View full text Add to dashboard Cite

Cartilaginous fish are considered the most primitive living jawed vertebrates with a complex immune system typical of all jawed vertebrates. Cytokine homologs are found within jawless and bony fish, although no cytokine or cytokine receptor genes have been sequenced in cartilaginous fish. In this study the complete coding sequence of the small spotted catshark (Scyliorhinus canicula) IL-1β gene is presented that contains a short 5′ untranslated region (54 bp), a 903-bp open reading frame, a 379-bp 3′ untranslated region, a polyadenylation signal, and eight mRNA instability motifs. The predicted translation (301 amino acids) has highest identity to trout IL-1β (31.7%), with greatest homology within the putative 12 β-sheets. The IL-1 family signature is also present, but there is no apparent signal peptide. As with other nonmammalian IL-1β sequences, the IL-1-converting enzyme cut site is absent. Expression of the IL-1β transcript is detectable by RT-PCR in the spleen and testes, induced in vivo with LPS. Furthermore, a 7-fold increase of transcript levels in splenocytes incubated for 5 h with LPS was seen. The genomic organization comprises six exons and five introns with highest homology seen in exons encoding the largest amount of secondary structure per amino acid. Southern blot analysis suggests at least two copies of the IL-1β gene or genes related to the 3′ end of the IL-1β sequence are present in the catshark. The cloning of IL-1β in S. canicula, the first cytokine sequenced within cartilaginous fish, verifies previous bioactivity evidence for the presence of inflammatory cytokines.

show abstract

Cloning of two chemokine receptor homologs (CXC-R4 and CC-R7) in rainbow trout Oncorhynchus mykiss

Cited by 58 publications

References 31 publications

Characterization of C–C chemokine receptor subfamily in teleost fish

Characterization of C–C chemokine receptor subfamily in teleost fish

Molecular cloning and genomic structure of an interleukin-8 receptor-like gene from homozygous clones of rainbow trout (Oncorhynchus mykiss)

The First Cytokine Sequence Within Cartilaginous Fish: IL-1β in the Small Spotted Catshark (Scyliorhinus canicula)

Contact Info

Product

Resources

About