This theoretical work investigates the properties of nonlinearlyoperated weakly-coupled resonators (WCRs) for resonant sensing applications. We propose an analysis framework for mutually injection-locked oscillators (MILOs) and mode-localized oscillators (MOLOs), subject to nonlinear restoring and damping forces. Under some simplifying assumptions, three sensor architectures are investigated and compared, highlighting several common features such as: (i) the insensitivity of the amplitude ratio output metric to the Af effect, (ii) the instability of one oscillation state above a threshold amplitude. These results are illustrated and validated using transient simulations. Their range of validity is then discussed with respect to finite perturbations, finite bandwidth, measurement noise and nonlinear dissipation-fluctuation. While nonlinear operation of WCRs has been experimentally investigated in [9, 14-15], and nonlinear coupling of FM resonant sensors or oscillators was covered in [16], there is little theoretical background against which experimental results obtained with nonlinear WCRs can be tested. Our own work on this subject [9, 17] has highlighted that some MILOs may benefit from nonlinear operation. In particular, the increase of the measurement range of MILOs, with a trade-off in sensitivity, was theoretically and experimentally proven in [9]. Most interestingly, the analysis in [17] showed the resolution of a MILO based on two similar Duffing resonators may not be limited by the A-f effect [18] provided amplitude-ratio was used as an output metric instead of phasedifference. To this day, no similar study has been performed on MOLOs. Furthermore, the results in [17] are limited to a narrow framework: a specific MILO architecture, only nonlinear restoring forces and quasi-static perturbations being considered. With this paper, we establish the fundamental limitations of WCRs in the nonlinear regime, aiming at a general, qualitative description of their behavior, rather than at particular results. The analysis of WCRs presented in section II may be used for MILOs or MOLOs; it is slightly simplified compared to the one in [17], but is more general in the sense that it captures dynamic system fluctuations (i.e. finite sensor bandwidth). Furthermore, it is not only valid for resonators with nonlinear restoring forces (e.g stress-stiffening, or electrostatic softening [19]), but also with nonlinear damping forces. Nonlinear damping is ubiquitous in MEMS sensors: for instance, it may result from the squeezed-film phenomenon [20], from anchor loss [21], or from coupling to an undesired vibration mode [22]. A global outlook on the nonlinear properties of WCRs with quadratic stiffness and damping coefficients is derived in sections III and IV. In section III, three WCR architectures are investigated, and their properties are established with further simplifying assumptions. We find that the insensitivity of AM WCRs to the A-f effect holds in all the studied cases. In section IV, these results are illustrated and ...