“…Compared to usual care in the UK, for every 1,000 fragility fracture patients assessed by the FLS, 18 fractures (including 11 hip fractures) will be prevented, with net cost-saving of £21,000 (€23,350, US$ 34,700) after taking into account all costs including costs of treatments [84]. In the UK, the Department of Health accepted the following arguments: based on the evidence (1) that half of hip fracture patients have suffered prior fractures [14][15][16][17] and (2) 16% of post-menopausal women have sustained a fracture [11][12][13], it follows that a FLS provides an opportunity for early intervention for half of all potential future cases of hip fracture by targeting only one sixth of the post-menopausal population. Cost savings from national implementation of FLS, potentially amount to £8.5 million over 5 years.…”