Clostridal infection of the uterus. A review treatment with hyperbaric oxygen

Hanson, Gillian C.; Slack, W. K.; Chew, H. E. R.; Thomas, DL

doi:10.1136/pgmj.42.490.499

Cited by 9 publications

(5 citation statements)

References 15 publications

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“…3 The use of hyperbaric oxygen (HBO) treatment may help as an adjuvant therapy prior to and after surgery. 4 Its use has been shown to decrease toxemia and produce improvement within 6 hours of treatment.…”

Section: Discussionmentioning

confidence: 99%

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A rare case of gas under diaphragm due to spontaneous perforation of uterus due to gas gangrene of uterus with clostridium perfringens infection presenting as intestinal perforation

Harika¹,

Rao²,

Sireesha³

et al. 2019

Int Surg J

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Uterine perforation is an uncommon, perforation due to clostridium perfringens is very rare, but potentially serious complication of uterine gangrene is due to clostridial infection, uterine manipulation, evacuation of retained products, termination of pregnancy, during coil insertion and hysteroscopic procedures. We report a 60 year old female patient presented with abdominal pain, constipation and Fever with features of septic shock. X-ray showed free gas under both domes of diaphragm. CT showed gas under diaphragm and hollow viscus perforation. This report aims to alert surgeons to the possibility that perforation of uterus due to gangrene with clostridium perfringens infection also shows air under diaphragm apart from routine causes. Correct diagnosis and treatment is essential for the survival of the patients with gas under diaphragm due to gas gangrene of uterus.

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Section: Discussionmentioning

confidence: 99%

“…3 The use of hyperbaric oxygen (HBO) treatment may help as an adjuvant therapy prior to and after surgery. 4 The proper diagnosis and early use of aggressive antibiotics and emergent surgery can decrease the mortality seen from clostridial sepsis. 1…”

Section: Introductionmentioning

confidence: 99%

A rare case of gas under diaphragm due to spontaneous perforation of uterus due to gas gangrene of uterus with clostridium perfringens infection presenting as intestinal perforation

Harika¹,

Rao²,

Sireesha³

et al. 2019

Int Surg J

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show abstract

“…HBO therapy can be used prior to and after surgical treatment. 8 Its use has been shown to decrease toxemia and produce improvement within 6 hours of treatment.…”

Section: Discussionmentioning

confidence: 99%

Uterine Perforation with Intra-Abdominal Clostridium perfringens Gas Gangrene: A Rare and Fatal Infection

Kashan

Muthu

Chaucer

et al. 2016

Journal of Gynecologic Surgery

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Background: Clostridium perfringens gas gangrene is an extremely rare and fatal infection. Necrosis of the myometrium is rarely seen and has only been recorded in 18 cases to date. Of these 18 reported cases, only 5 have occurred in nonpregnant women. This article presents the 6th case of myometrium necrosis from C. perfringens. Case: A 72-year-old woman, gravida 2, para 2, presented with abdominal pain and vaginal bleeding. After examinations, laboratory testing, and several surgical interventions, she was found to have C. perfringens infection and advanced high-grade serous adenocarcinoma of the endometrium with >50% invasion into the myometrium. Results: Despite the surgical interventions and use of several antibiotics, this patient did not improve. She was weaned from treatment per her advance directive and died after weaning. Conclusions: Awareness of the many etiologies for peritonitis is of great importance when a fatal infection may be the cause of the condition. Correct diagnosis and proper treatment is essential for the survival of patients infected with C. perfringens. (J GYNECOL SURG 32:182)

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“…Blood loss should not be replaced with blood unless severe, since the oxygen transport capacity is highest at a haematocrit value of around 30 % (Hint, 1968). Should a circulating haemolysin be present, blood replacement should be delayed for a few hours if possible until the antibiotics have begun to take effect hyperbaric oxygen appears to eliminate haemolysis in clostridial infections, and hyperbaric oxygen therapy should be given before blood in cases of clostridial septicaemia (Hanson et al, 1966).…”

Section: Comments Ventilationmentioning

confidence: 99%

“…Hyperbaric oxygen therapy is indicated in all severe cases of clostridial infection and dramatically relieves toxaemia and septic shock (Hanson et al, 1966).…”

Clostridal infection of the uterus. A review treatment with hyperbaric oxygen

Cited by 9 publications

References 15 publications

A rare case of gas under diaphragm due to spontaneous perforation of uterus due to gas gangrene of uterus with clostridium perfringens infection presenting as intestinal perforation

A rare case of gas under diaphragm due to spontaneous perforation of uterus due to gas gangrene of uterus with clostridium perfringens infection presenting as intestinal perforation

Uterine Perforation with Intra-Abdominal Clostridium perfringens Gas Gangrene: A Rare and Fatal Infection

Septicaemic shock. Report of three cases: a review of diagnosis and management

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