1987
DOI: 10.1001/archsurg.1987.01400180037007
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Clostridium difficile Diarrhea in Critically Ill Burned Patients

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Cited by 34 publications
(15 citation statements)
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“…Based on older studies [23,24], C. difficile infection is always suspected when diarrhoea occurs in the ICU, mainly in patients with antibiotics [25]. In our tertiary ICU, a low incidence of C. difficile infection (0.7%) was observed.…”
Section: Discussionmentioning
confidence: 86%
“…Based on older studies [23,24], C. difficile infection is always suspected when diarrhoea occurs in the ICU, mainly in patients with antibiotics [25]. In our tertiary ICU, a low incidence of C. difficile infection (0.7%) was observed.…”
Section: Discussionmentioning
confidence: 86%
“…Administration of systemic antibiotic therapy may also cause antibiotic-associated diarrhea due to the overgrowth of toxigenic strains of Clostridium difficile (176,404,415). Exposure to prophylactic antibiotic therapy may also increase the resistance of endogenous and pathogenic bacteria to a wide variety of antibiotics, making the subsequent treatment of clinically overt infections in the burn patient more difficult (6,307).…”
Section: Prophylactic Systemic Antibioticsmentioning
confidence: 99%
“…Critically ill burn patients are particularly at risk for pseudomembranous colitis because of altered gastrointestinal flora and motility, exposure to mUltiple antibiotics and a severely immunocompromised state (Grube et al 1987). Uraemic patients also have impaired immune response and intestinal motility, which may be predisposing factors (Leung et al 1985).…”
Section: Risk Factorsmentioning
confidence: 99%