Clostridium perfringens Spontaneous Bacterial Peritonitis: Report of a Case and Implications for Management

A Rare Case of Secondary Bacterial Peritonitis fromClostridium perfringensin an Adult Patient with Noncirrhotic Ascites and a Krukenberg Tumor: Report of a Case

“…Isolation of Clostridium perfringens as a cause of spontaneous bacterial peritonitis (SBP) is an extremely rare, though known, event with only a mere handful of cases reported in the literature [3–7]. Most cases of SBP are detailed in patients with cirrhosis, especially Child-Pugh class C, whom have ascites, and greater than 60% of cases are secondary to Gram-negative enteric bacteria ( Escherichia coli and Klebsiella-pneumoniae ).…”

Spontaneous Bacterial Peritonitis with Septicemia withProvidencia rettgeriandClostridium perfringens

“…The organisms responsible for SBP are isolated in 60-70% of cases [1], and are generally gut bacteria such as Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis [2]. To the best of our knowledge, there are no reports of SBP caused by Providencia rettgeri and few reports of SBP caused by Clostridium perfringens [4]. Here we report a suspicious case of SBP with sepsis caused by both P. rettgeri and C. perfringens.…”

Spontaneous bacterial peritonitis by Clostridium species and antimicrobial therapy

“…Anaerobes rarely cause SBP although they are predominant in the small intestine and colon, probably because of high oxygen tension of the ascetic fluid and relative inability to cross intestinal mucosa. Achlorhydria and decreased intestinal motility cause small intestinal bacteria overgrowth, which can cause SBP by bacterial translocation [ 5 ].…”