2014
DOI: 10.1016/j.idcr.2014.06.003
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Clostridium subterminale septicemia in a patient with esophageal cancer

Abstract: Clostridium subterminale (C. subterminale) is a pathogenic species of Clostridium that has been infrequently isolated. We report a case of C. subterminale bacteremia causing sepsis in a patient with metastatic gastrointestinal malignancy.

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Cited by 8 publications
(11 citation statements)
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“…are the second most common cause of anaerobic bacteremia after Bacteroides spp with C. perfringens being the most commonly isolated species in the blood, followed by C. septicum [2] . To our knowledge, C. subterminale bacteremia has been previously reported only in three immunocompromised adult patients [3] , [4] , [5] .…”
Section: Introductionmentioning
confidence: 80%
See 1 more Smart Citation
“…are the second most common cause of anaerobic bacteremia after Bacteroides spp with C. perfringens being the most commonly isolated species in the blood, followed by C. septicum [2] . To our knowledge, C. subterminale bacteremia has been previously reported only in three immunocompromised adult patients [3] , [4] , [5] .…”
Section: Introductionmentioning
confidence: 80%
“…He had undergone endoscopic placement of an esophageal stent and underwent repeat endoscopy one week later because of suspected stent migration. A few days after the last endoscopy he was admitted with signs of infection and a blood culture grew C. subterminale [5] . In all the above cases there was evidence of mucosal damage which may have facilitated entry of C. subterminale into the bloodstream from the patients’ gut microflora.…”
Section: Discussionmentioning
confidence: 99%
“… 7 C. subterminale has been previously reported in immunocompromised patients undergoing chemotherapy, with three bacteremia cases reported. 8-10 A separate case of bacteremia in an immunocompetent patient was found after an esophageal rupture. 11 Additionally, there were two cases reported C. subterminale in pleuropulmonary infections, two cases of soft tissue infection, and one case in an open fracture.…”
Section: Discussionmentioning
confidence: 98%
“…Sources of C. subterminale include but are not limited to abscesses, blood, and wounds. One case report of C. subterminale septicemia in a patient with esophageal cancer stated that the likely source of the C. subterminale infection was mucosal manipulation during stent placement or repeat endoscopy [ 5 ]. Another report described C. subterminale septicemia potentially from ulceration near the distal edge of the anal canal in a 51-year-old patient with acute lymphoblastic leukemia [ 6 ].…”
Section: Discussionmentioning
confidence: 99%