Closure of patent ductus arteriosus in children, small infants, and premature babies with Amplatzer duct occluder II additional sizes: Multicenter study

Sungur, Metin; Karakurt, Cemşit; Özbarlas, Nazan; Başpınar, Osman

doi:10.1002/ccd.24905

Cited by 50 publications

(39 citation statements)

References 30 publications

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“…Evidence on the risks of drug therapy or surgical PDA ligation26, 27 has led to growing interest in the use of percutaneous closure in premature infants 10, 15, 16, 28, 29, 30. The main finding of our 10‐year study is that, among a large cohort of infants born very premature and referred for percutaneous closure at weights <4 kg, the majority are successfully closed in the catheterization suite with evidence of improved pulmonary status following closure, but risk of arterial injury in these infants is noteworthy.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications

Backes

Cheatham

Deyo

et al. 2016

JAHA

110

111

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BackgroundPercutaneous closure of patent ductus arteriosus (PDA) in term neonates is established, but data regarding outcomes in infants born very preterm (<32 weeks of gestation) are minimal, and no published criteria exist establishing a minimal weight of 4 kg as a suitable cutoff. We sought to analyze outcomes of percutaneous PDA occlusion in infants born very preterm and referred for PDA closure at weights <4 kg.Methods and ResultsRetrospective analysis (January 2005–January 2014) was done at a single pediatric center. Procedural successes and adverse events were recorded. Markers of respiratory status (need for mechanical ventilation) were determined, with comparisons made before and after catheterization. A total of 52 very preterm infants with a median procedural weight of 2.9 kg (range 1.2–3.9 kg) underwent attempted PDA closure. Twenty‐five percent (13/52) of infants were <2.5 kg. Successful device placement was achieved in 46/52 (88%) of infants. An adverse event occurred in 33% of cases, with an acute arterial injury the most common complication. We observed no association between weight at time of procedure and the risk of an adverse event. No deaths were attributable to the PDA closure. Compared to precatheterization trends, percutaneous PDA closure resulted in improved respiratory status, including less exposure to mechanical ventilation (mixed effects logistic model, P<0.01).ConclusionsAmong infants born very preterm, percutaneous PDA closure at weights <4 kg is generally safe and may improve respiratory health, but risk of arterial injury is noteworthy. Randomized clinical trials are needed to assess clinically relevant differences in outcomes following percutaneous PDA closure versus alternative (surgical ligation) management strategies.

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Section: Discussionmentioning

confidence: 99%

Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications

Backes

Cheatham

Deyo

et al. 2016

JAHA

110

111

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show abstract

“…On the other hand, the ADO II AS was largely preferred for premature patients because of its low profile; its sheath size, which is sufficient for 4F catheters; and advantages of its use in tubular PDAs (Fig. ) . The Cook coil, Nit‐Occlud coil, vascular plug, and muscular ventricular septal occluder were used in a fewer patients.…”

Section: Methodsmentioning

confidence: 99%

“…In infants <6 months of age, and in particular in preterm infants, standard surgery has been proposed for PDA closure . A limited number of studies have examined transcatheter closure of PDAs performed in young and premature infants . Here, we present our findings regarding our use of different devices for transcatheter closures of a PDA in infants <6 kg over the past 5 years, and PDA closures in premature infants over the last 2 years.…”

Section: Introductionmentioning

confidence: 99%

Transcatheter Closure of Patent Ductus Arteriosus in Under 6 kg and Premature Infants

Başpınar

Şahin

Sülü

et al. 2015

J Interven Cardiology

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“…Limited numbers of human studies concerning the use of this device are present. One of these reports is a multicenter study, which explains the percutaneous PDA closure with ADO II-AS device in children (16). They have explained that the ADO II AS device could be used for all types of PDA less than 4 mm in the children of different ages.…”

Section: Discussionmentioning

confidence: 99%

Transcatheter closure of PDA in premature babies less than 2 kg

et al. 2016

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Objective:Our hypothesis was that percutaneous PDA closure in babies less than 2 kg was a safe and effective method. The aim of this study is to share our experience in transcatheter PDA closure in infants whose body weight is less than 2 kg in order to support our hypothesis.Methods:Between July 1997 and October 2014, 382 percutaneous PDA closures were done in our center. Nineteen patients who weighed less than 2 kg were included in this retrospectively study. The other inclusion criteria were 1) being symptomatic and PDA was thought as a possible contributor of medical state and 2) persistence of PDA after medical closure treatment. Patients who had sepsis and bleeding diathesis were excluded. According to size and shape of PDA, different types of devices were used such as detachable coils and Amplatzer duct occluders. Data was expressed as mean (SD) or median (minimum–maximum). Comparisons of means and medians were performed with Student’s t-test and with Mann–Whitney U test, respectively.Results:The median patient age and weight were 32 days and 1603 g (range 910–2000 g) respectively. Mean PDA diameter was 3.2±1.3 mm. Morphology of PDA was type A in 7 patients, type C in 10, type E in 1, and type B in 1 patient. There were no reported major complications. Stenosis of left pulmonary artery was detected in four patients, all of which resolved in 6 months follow-up.Conclusion:Percutaneous PDA closure in babies less than 2 kg is a safe and effective method that can be an alternative to surgery. Main distinguishing feature of this study is that it includes the largest cohort of patients less than 2 kg whose PDA closed percutaneously.

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Closure of patent ductus arteriosus in children, small infants, and premature babies with Amplatzer duct occluder II additional sizes: Multicenter study

Abstract: Our study shows that closure of medium and small sized PDA by using ADO II AS device is effective and safe in children. The use of the device will expand the field of application of PDA closure in small infants.

Cited by 50 publications

References 30 publications

Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications

Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications

Transcatheter Closure of Patent Ductus Arteriosus in Under 6 kg and Premature Infants

Transcatheter closure of PDA in premature babies less than 2 kg

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