Closure of tympanic membrane perforations using repeated trichloracetic acid

Gür, Özer Erdem; Ensarı, Serdar; Sonbay, Nevreste Didem; Ensari, Nuray; Celikkanat, Serdar; Boztepe, Osman Fatih

doi:10.5455/medscience.2016.05.8428

Cited by 1 publication

(1 citation statement)

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“…6 The use of 50% and near-saturated TCA solutions was reported with successful results. 6,7 This study was designed to determine whether the short and long-term mechanical strength of GIBC could be increased with a pre-treatment in a rat model. As far as we know, this is the first study in the otorhinolaryngology literature that incorporates mechanical tests to determine and compare the longterm durability of bone cement applications.…”

Section: Original Researchmentioning

confidence: 99%

Comparison of the Bond Strengths of Glass-Ionomer Bone Cement Combined with Various Pretreatments

ERGÜN,

HAKAN YÜCE,

ÇAKMAK

et al. 2023

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ABS TRACT Objective: Our aim in this study is to determine if a pretreatment could make bone cement connection stronger and reduce the failure rate. Material and Methods: Twenty-four 6-9 months old female rats were divided into 2 groups as "day 0" and "day 90". Four different applications were made to the 2x2 cm 2 surgical area. Freshly prepared glass ionomer bone cement (GIBC) was applied by removing the periosteum with bipolar in the first application, by keeping the perichondrium intact in the second application, by removing the periosteum with trichloroacetic acid (TCA) solution in the third application, and by removing the periosteum mechanically in the last application. After these rats were sacrificed on day 0 and day 90, mechanical tests were made to the bone cements and shear strength values were calculated by dividing the maximum measured forces by the apparent contact areas. Results: Although shear forces were higher on day 90 than on day 0 (p=0.007), subgroup analyses revealed that the differences were significant in only the subperiosteum group (p=0.003). According to the pairwise comparisons, subperiosteal bone cement application yielded significantly higher shear forces on day 90 compared to the others (p<0.003) while the supraperiosteum, TCA, and electrocoagulation groups were similar to each other. Conclusion: GIBC reached its highest shear strength with time after a subperiosteal application. We do not recommend any of the pre-treatments tried in this study over a supra periosteal application before a bone cement ossiculoplasty since no increase in shear strength could be obtained.

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Section: Original Researchmentioning

confidence: 99%