In June–July 2020, the middle and lower reaches of the Yangtze River (MLYR) were hit by a Meiyu event characterized by a long duration, abundant precipitation, and frequent heavy rainfall, resulting in destructive flooding. We found that the extreme cumulative precipitation in 2020 was mainly contributed by more moderate to heavy daily precipitation rather than extreme daily events. Although some previous studies have been conducted to attribute the 2020 Meiyu event in the MLYR, most of them focused on the cumulative precipitation amount. This attribution case study complements previous attribution analyses and reveals many new features. Our results show that anthropogenic climate change—primarily driven by greenhouse gas (GHG) forcing, anthropogenic aerosol (AA) forcing, and land‐use—has led to a decrease in the number of light to heavy precipitation days, while concurrently increasing the number of extreme precipitation days in the MLYR. Specifically, GHG and AA forcings decreased the frequency of light and moderate precipitation, but only GHG increased the frequency of extreme precipitation. An increasing trend in very heavy precipitation days has been observed. The competitive effects of GHG and AA forcings make it challenging to detect the signal of human activities, which could be intermingled with effects from natural variability. Under the SSP5‐8.5 scenario, the probability of experiencing both light and extreme precipitation events will significantly increase in the MLYR. By 2050–2100, these events are projected to be nearly 4 times more frequent compared to the current climate, which poses significant challenges to water security and economic development decision makers.