CLOX Executive Clock Drawing Task

Royall, Donald R.; Cordes, Jeffrey A.; Polk, Marsha J.

doi:10.1037/t05136-000

Cited by 212 publications

(336 citation statements)

References 12 publications

Supporting

Mentioning

312

Contrasting

Unclassified

Order By: Relevance

“…Phonemic fluency impairment can indicate that this circuit is disrupted at one or more of these subcortical loci or in the white matter tracts that interconnect them with the dorsolateral prefrontal lobe 21 . Royall et al 16 described that CLOX 1 places high demands on executive control functioning, since patients are required to perform in a novel context, whereas CLOX 2 represents a purer measure of visoconstructional ability. However, their study included only patients with AD, together with a control group, but not patients with subcortical dementia.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Limitations in differentiating vascular dementia from Alzheimer's disease with brief cognitive tests

Matioli

Caramelli

2010

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Objective: To investigate the diagnostic value of brief cognitive tests in differentiating vascular dementia (VaD) from Alzheimer's disease (AD). Method: Fifteen patients with mild VaD, 15 patients with mild probable AD and 30 healthy controls, matched for age, education and dementia severity, were submitted to the following cognitive tests: clock drawing (free drawing and copy), category and letter fluency, delayed recall test of figures and the EXIT 25 battery. Results: VaD patients performed worse than AD patients in category fluency (p=0.014), letter fluency (p=0.043) and CLOX 2 (p=0.023), while AD cases performed worse than VaD patients in delayed recall (p=0.013). However, ROC curves for these tests displayed low sensitivity and specificity for the differential diagnosis between VaD and AD. Conclusion: Although the performance of VaD and AD patients was significantly different in some cognitive tests, the value of such instruments in differentiating VaD from AD proved to be very limited. Key words: Alzheimer's disease, vascular dementia, clock drawing test, delayed recall, diagnosis, EXIT25, neuropsychological tests, verbal fluency.Limitações em diferenciar demência vascular de doença de Alzheimer através de testes cognitivos breves RESUMO Objetivo: Investigar o valor diagnóstico de testes cognitivos breves na diferenciação de demência vascular (DV) e doença de Alzheimer (DA). Método: Quinze pacientes com DV, 15 com DA provável e 30 controles saudáveis, pareados em relação à idade, escolaridade e gravidade da demência, foram submetidos aos seguintes testes: desenho do relógio espontâneo e cópia, fluência verbal semântica e fonêmica, teste de evocação de memória de figuras e a bateria EXIT25. Resultados: Pacientes com DV apresentaram pior desempenho na fluência verbal semântica (p=0,014), fonêmica (p=0,043), e no CLOX 2 (p=0,023). O grupo com DA obteve pior desempenho no teste de evocação tardia (p=0,013). As curvas ROC aplicadas a esses testes mostraram baixa sensibilidade e especificidade para o diagnóstico diferencial entre DV e DA. Conclusão: Embora o desempenho dos pacientes tenha sido diferente em alguns testes, o valor desses instrumentos para o diagnóstico diferencial entre DV e DA parece ser muito limitado. Palavras-chave: doença de Alzheimer, demência vascular, teste do desenho do relógio, memória de evocação, diagnóstico, EXIT25, testes neuropsicológicos, fluência verbal.

show abstract

Section: Resultsmentioning

confidence: 99%

“…); phonemic verbal fluency (F-A-S); Executive clock drawing task (CLOX 1= on free drawing and CLOX 2=on copy) 16 .…”

Section: Methodsmentioning

confidence: 99%

Limitations in differentiating vascular dementia from Alzheimer's disease with brief cognitive tests

Matioli

Caramelli

2010

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…These were: the Executive Interview (EXIT25) [27], Clock Drawing (CLOX 1) [28] and the Controlled Oral Word Association Test (COWAT) of verbal fluency [3].…”

Section: Introductionmentioning

confidence: 99%

“…CLOX 2 [28] and the COWAT of category fluency [3] were used to assess visuospatial function and semantic fluency respectively.…”

Section: Introductionmentioning

confidence: 99%

Apolipoprotein ɛ4 and neuropsychological performance in Alzheimer's disease and vascular dementia

Carson¹,

Barrett²,

Craig³

et al. 2010

Neuroscience Letters

View full text Add to dashboard Cite

“…The cognitive screening (brief cognitive battery) included tests on memory and executive functions; a delayed recall test 11 ; category verbal fluency; phonemic verbal fluency; and an executive clock drawing task (CLOX) 12 . The patients selected were assessed for particular cognitive traits using the Mattis Dementia Rating Scale (MDRS) 13 , with five subscales analyzing distinct cognitive domains: attention, initiative/perseverance, construction, concept and memory.…”

Section: Technical Informationmentioning

confidence: 99%

Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension

Schelp

Mendes-Chiloff

Bazan

et al. 2012

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

OBJECTIVE: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients. METHODS: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated. RESULTS: There was no significant effect from the presence of hypertension (OR=2.36 for patients under 65 years old and OR=0.64 for patients over 65), diabetes or hypercholesterolemia regarding occurrences of dementia associated with PD (24% of the patients). The study demonstrated that each year of age increased the estimated risk of dementia in PD patients by 9% (OR=1.09; 95%CI: 1.01-1.17). CONCLUSION: There was no evidence to correlate the presence of metabolic syndrome with the risk of dementia that was associated with PD. The study confirmed that dementia in PD is age dependent and not related to disease duration.

show abstract

CLOX Executive Clock Drawing Task

Cited by 212 publications

References 12 publications

Limitations in differentiating vascular dementia from Alzheimer's disease with brief cognitive tests

Limitations in differentiating vascular dementia from Alzheimer's disease with brief cognitive tests

Apolipoprotein ɛ4 and neuropsychological performance in Alzheimer's disease and vascular dementia

Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension

Contact Info

Product

Resources

About