Abstract:Purpose: Clozapine has been reported to be effective for refractory schizophrenic patients. However, there have been few reports investigating whether clozapine responders are likely to suffer from more or fewer extrapyramidal symptoms. The aim of the present study is to investigate the association between clinical effects of clozapine and extrapyramidal symptoms in clozapine-treated patients. Methods: Ten patients were divided into Improvement Group with CGI-I scores ranging from 1 to 3 and Non-improvement Gr… Show more
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