This paper investigates the performance of the micro-electro-mechanical systems resonant sensor used for particle detection and concentration measurement. The fine and ultra-fine particles such as particulate matter (PM), ferrous particles, and nanoparticles are known to contaminate the atmosphere, fluids used in industrial machines, and food, respectively. The physical principles involved in the target particles accumulating on the sensor are presented. Micro-gravimetric resonators that use piezoelectric and thermally actuated transducers for particle detection and concentration measurement in air and high-viscosity liquids are analyzed. Critical sensor features, such as maximum possible parametric sensitivity, the detection limit of particle size and mass concentration, linear dynamic range, and output stability, are thoroughly evaluated.