Co-detection of isoprenaline and paracetamol in biological and pharmaceutical media by a feather-like La3+/ZnO nano-flowers and N-(ferrocenylmethylidene)fluoren-2-amine-modified carbon paste electrode: analysis of a novel sensor

Pourtaheri, Ehsan; Taher, Mohammad Ali; Beitollahi, Hadi; Hosseinzadeh, Rahman

doi:10.1007/s13738-020-01870-w

Cited by 4 publications

(1 citation statement)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the modifiers used, some ligands and novel compounds can be considered potent modifiers recommended to researchers in the future [20–24] . Electrochemical techniques with high sensitivity, low cost, ease of modification of the electrode surface in more cases, and relatively short analysis time characteristics have been commonly referred to as other analytical techniques and used in the detection/determination of different organic and inorganic chemicals [25–47] . Among the chemical compounds, anticancer drugs are highly electroactive due to their structural OH and NH2 functional groups.…”

Section: Introductionmentioning

confidence: 99%

The Experimental Design Approach in Square‐Wave Voltammetric Determination of Tamoxifen by NiO‐CPE**

Raeisi‐Kheirabadi

Nezamzadeh‐Ejhieh

2022

ChemistrySelect

View full text Add to dashboard Cite

Due to the explosive global increase of various cancers, the need to introduce/develop novel catalysts/sensors for quantitative determination of cancer drugs is emphasized. Nickel oxide nanoparticles (NiO‐NPs) calcined at 200 °C were used as a modifier of carbon paste electrode (CPE) to quantify tamoxifen (TAM) in an aqueous solution. The square wave voltammetry (SqW) was used due to its high sensitivity. The modified NiO‐CPE showed an SqW anodic peak current with a peak potential of about 420 mV in the NaOH‐supporting electrolyte. This peak current was decreased when TAM analyte was added to the test solution. Thus, this reduced peak current (Δi) was used to quantify TAM in solution. The experimental design used the response surface methodology (RSM) approach to study the simultaneous interaction effects between the influencing variables. The optimized run was associated with a 10 % NiO ingredient in the CPE, 0.3 M NaOH, an amplitude of 200 mV, a step potential of 3 mV, and a frequency of 25 Hz. A proportional behavior was obtained between the mentioned Δi and TAM concentration in the range of 10–60 nM. The detection (LOD) and quantification (LOQ) limits were 1.81±0.35 and 6.05±0.24 nM, respectively. Interfering and recovery results confirmed the applicability of the proposed NiO‐CPE electrode for TAM determination in complex matrixes and the direct assay of the drug in human serum.

show abstract

Section: Introductionmentioning

confidence: 99%