Co-localisation of abnormal brain structure and function in specific language impairment

Badcock, Nicholas A.; Bishop, Dorothy V. M.; Hardiman, Mervyn J.; Barry, J; Watkins, Kate E.

doi:10.1016/j.bandl.2011.10.006

Cited by 133 publications

(186 citation statements)

References 58 publications

(61 reference statements)

Supporting

Mentioning

157

Contrasting

Unclassified

Order By: Relevance

“…This finding would be in line with previously reported motor (speech) disorders in galactosemia (Potter, 2011;Potter et al, 2013;Rubio-Agusti et al, 2013;Shriberg et al, 2011). Hypoactivity of the posterior STG and PT has been observed in patients with specific language impairment (SLI) (Badcock et al, 2012) and CAS as well (Liegeois et al, 2003). Weaker connectivity in patients between IFG and the right PT, and bilateral superior parietal regions supports this claim, suggesting suboptimal communication between frontal areas associated with overall language planning (IFG) and temporal and parietal sensory-motor integration (PT, superior parietal region).…”

Section: Discussionsupporting

confidence: 89%

Affected functional networks associated with sentence production in classic galactosemia

et al. 2015

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 89%

Affected functional networks associated with sentence production in classic galactosemia

et al. 2015

View full text Add to dashboard Cite

“…Moreover, dyslexic readers have been reported to not show the typical leftward asymmetry of the planum temporale (e.g., Hynd, SemrudClikeman, Lorys, Novey, & Eliopulos, 1990;Larsen, Høien, Lundberg, & Odegaard, 1990), although reports have been inconsistent (for a review, see Heim & Keil, 2004). Structural abnormalities of the planum temporale and surrounding areas have further been associated with other developmental speech and language disorders like specific language impairment (e.g., Badcock, Bishop, Hardiman, Barry, & Watkins, 2012) or stuttering (e.g., Foundas et al, 2004). We therefore interpret the significant positive relationship between left superior temporal gray matter volume and subsequent changes in reading proficiency as evidence for preexisting neurostructural differences, which might be associated with differences in general linguistic abilities.…”

Section: Discussionmentioning

confidence: 99%

The Association between Gray Matter Volume and Reading Proficiency: A Longitudinal Study of Beginning Readers

Linkersdörfer

Jurcoane

Lindberg

et al. 2015

Journal of Cognitive Neuroscience

View full text Add to dashboard Cite

Abstract■ Neural systems involved in the processing of written language have been identified by a number of functional imaging studies. Structural changes in cortical anatomy that occur in the course of literacy acquisition, however, remain largely unknown. Here, we follow elementary school children over their first 2 years of formal reading instruction and use tensor-based morphometry to relate reading proficiency to cortical volume at baseline and follow-up measurement as well as to intraindividual longitudinal volume development between the two measurement time points. A positive relationship was found between baseline gray matter volume in the left superior temporal gyrus and subsequent changes in reading proficiency. Furthermore, a negative relationship was found between reading proficiency at the second measurement time point and intraindividual cortical volume development in the inferior parietal lobule and the precentral and postcentral gyri of the left hemisphere. These results are interpreted as evidence that reading acquisition is associated with preexisting structural differences as well as with experiencedependent structural changes involving dendritic and synaptic pruning. ■

show abstract

“…It is highly heritable, and so far several risk genes and copy-number variants have been identified (Deriziotis & Fisher, 2013;Simpson et al, 2015). Neuroimaging studies of individuals with SLI have revealed structural and functional differences in left frontal and temporal regions associated with language as well as in basal ganglia structures (Badcock, Bishop, Hardiman, Barry, & Watkins, 2012;van der Lely & Pinker, 2014). Despite how common the disorder is, there has been relatively little systematic research on the neural systems that underlie language impairment in SLI, and most published studies include small sample sizes and different methodologies.…”

Section: Slimentioning

confidence: 99%

Risk Factors Associated With Language in Autism Spectrum Disorder: Clues to Underlying Mechanisms

Tager–Flusberg

2016

J Speech Lang Hear Res

View full text Add to dashboard Cite

a Purpose: Identifying risk factors associated with neurodevelopmental disorders is an important line of research, as it will lead to earlier identification of children who could benefit from interventions that support optimal developmental outcomes. The primary goal of this review was to summarize research on risk factors associated with autism spectrum disorder (ASD). Method: The review focused on studies of infants who have older siblings with ASD, with particular emphasis on risk factors associated with language impairment that affects the majority of children with ASD. Findings from this body of work were compared to the literature on specific language impairment.Results: A wide range of risk factors has been found for ASD, including demographic (e.g., male, family history), behavioral (e.g., gesture, motor) and neural risk markers (e.g., atypical lateralization for speech and reduced functional connectivity). Environmental factors, such as caregiver interaction, have not been found to predict language outcomes. Many of the risk markers for ASD are also found in studies of risk for specific language impairment, including demographic, behavioral, and neural factors. Conclusions: There are significant gaps in the literature and limitations in the current research that preclude direct cross-syndrome comparisons. Future research directions are outlined that could address these limitations.

show abstract

Co-localisation of abnormal brain structure and function in specific language impairment

Cited by 133 publications

References 58 publications

Affected functional networks associated with sentence production in classic galactosemia

Affected functional networks associated with sentence production in classic galactosemia

The Association between Gray Matter Volume and Reading Proficiency: A Longitudinal Study of Beginning Readers

Risk Factors Associated With Language in Autism Spectrum Disorder: Clues to Underlying Mechanisms

Contact Info

Product

Resources

About