Co‐occurrence of Obsessive‐Compulsive Personality Traits in Young and Middle‐Aged Japanese Alcohol‐Dependent Men

Suzuki, Kenji; Muramatsu, Taro; Takeda, Aya; Shirakura, Katsuyuki

doi:10.1111/j.1530-0277.2002.tb02659.x

Cited by 17 publications

(1 citation statement)

References 32 publications

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“…Obsesivnokompulzivna simptomatika, vezana na zaužitje alkohola, je bila pri njih tudi izrazitejša in je odražala še prisotno hrepenenje po alkoholu, kar so ugotavljali tudi v japonski raziskavi (32). Hrepenenje po alkoholu je lahko pomembnejši dejavnik tveganja kot depresivno razpoloženje, medtem ko oba povečata tveganje za uživanje alkohola ob sopojavni zasvojenosti ali zlorabi od alkohola (33,34).…”

Section: Razpravaunclassified

Expression of Symptoms of the Most Common Comorbid Mental Disorders in Slovenian Alcohol Addicted Patients

Plemenitas

Dolžan

Plesničar

2014

Slovenian Journal of Public Health

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IZVLEČEKKljučne besede: zasvojenost od alkohola, sopojavnost, vprašalniki, obsesivno-kompulzivni simptomi, anksioznost, depresivnost, agresivnost Izhodišča. Zasvojenost od alkohola je zelo pogosta in kompleksna bolezen. Zasvojeni od alkohola imajo veliko tveganje za pojav sopojavne psihiatrične motnje.Metode. V prvi tovrstni slovenski raziskavi smo preverili prisotnost in izraženost simptomatike najpogostejših sopojavnih duševnih motenj pri zasvojenih od alkohola. Vključili smo tri skupine moških: 101 preiskovanca, hospitaliziranega zaradi zdravljenja akutne zasvojenosti od alkohola, 100 abstinentnih preiskovancev in 97 zdravih kontrol iz skupine prostovoljnih krvodajalcev. Za oceno simptomatike smo uporabili vprašalnike AUDIT, Yale-Brownovo lestvico obsesivnosti in kompulzivnosti ter lestvico obsesivno-kompulzivnega pitja, Zungovo lestvico depresivnosti in anksioznosti, Kratko lestvico socialne fobije in Buss-Durkeejevo lestvico sovražnosti.Rezultati. V skupini preiskovancev z akutno zasvojenostjo so bili pomembno bolj izražene obsesivna (p < 0,001) in kompulzivna simptomatika (p < 0,001) ter obsesivno-kompulzivna simptomatika, vezana na pitje alkoholnih pijač (p < 0,001), kot v preostalih dveh skupinah. Pri preiskovancih z akutno zasvojenostjo so bile v primerjavi z abstinenti in zdravimi kontrolami statistično pomembno bolj izražene anksioznost (p < 0,001), depresivnost (p < 0,001) in agresivnost (p < 0,001).Zaključki. Obsesivno-kompulzivna simptomatika, anksioznost, depresivnost in agresivnost so lahko sopojavno vezane na zasvojenost od alkohola. Med zdravljenjem zasvojenosti od alkohola je zato treba pozornost usmeriti tudi na te simptome, saj tako lahko bistveno izboljšamo izid zdravljenja zasvojenosti od alkohola in zmanjšamo tveganje za relaps. ABSTRACT

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Section: Razpravaunclassified

Expression of Symptoms of the Most Common Comorbid Mental Disorders in Slovenian Alcohol Addicted Patients

Plemenitas

Dolžan

Plesničar

2014

Slovenian Journal of Public Health

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The Relationship Between Anxiety Disorders and Substance Use Among Adolescents in the Community: Specificity and Gender Differences

Goodwin

Fuller

et al. 2009

J Youth Adolescence

115

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Using a sample of 781 adolescents (ages 13–17, 52.8% male) from a community survey, this study examined gender differences in the co-occurrence of specific anxiety disorders with substance use in adolescents. The associations between anxiety disorders and substance use differed according to the particular anxiety disorders and forms of substance use being examined, as well as by gender. Social phobia was associated with cigarette smoking among boys only. For girls, social phobia appeared to be negatively associated with drug use. For the other anxiety disorders, the associations with substance use tended to be stronger among girls. These findings highlight the need to improve clinical recognition of the anxiety disorders and to improve treatment access for afflicted adolescents. Future studies based on longitudinal data could further elucidate the relationships among anxiety disorders, gender, and substance use.

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Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment

Perez

Biasi

2015

Alcohol

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Alcohol is one of the most prevalent addictive substances in the world. Withdrawal symptoms result from abrupt cessation of alcohol consumption in habitual drinkers. The emergence of both affective and physical symptoms produces a state that promotes relapse. Mice provide a preclinical model that could be used to study alcohol dependence and withdrawal while controlling for both genetic and environmental variables. The use of a liquid ethanol diet offers a reliable method for the induction of alcohol dependence in mice, but this approach is impractical when conducting high throughput pharmacological screens or when comparing multiple strains of genetically engineered mice. The goal of this study was to compare withdrawal associated behaviors in mice chronically treated with a liquid ethanol diet vs. mice treated with a short-term ethanol treatment that consisted of daily ethanol injections containing the alcohol dehydrogenase inhibitor, 4-methylpyrazole. Twenty-four hours after ethanol treatment, mice were tested in the open field arena, the elevated plus maze, the marble burying test or for changes in somatic signs during spontaneous ethanol withdrawal. Anxiety-like and compulsive-like behavior, as well as physical signs, were all significantly elevated in mice undergoing withdrawal, regardless of the route of ethanol administration. Therefore, a short-term ethanol treatment can be utilized as a screening tool for testing genetic and pharmacological agents before investing in a more time consuming ethanol treatment.

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Co‐occurrence of Obsessive‐Compulsive Personality Traits in Young and Middle‐Aged Japanese Alcohol‐Dependent Men

Abstract: Young and middle-aged male Japanese alcoholics have more obsessive-compulsive personality traits than nonalcoholic males of similar ages. Their alcohol-related psychological and behavioral characteristics may derive, in part, from their obsessive-compulsive symptoms.

Cited by 17 publications

References 32 publications

Expression of Symptoms of the Most Common Comorbid Mental Disorders in Slovenian Alcohol Addicted Patients

Expression of Symptoms of the Most Common Comorbid Mental Disorders in Slovenian Alcohol Addicted Patients

The Relationship Between Anxiety Disorders and Substance Use Among Adolescents in the Community: Specificity and Gender Differences

Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment

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