Co-Relation of 24 Hours Proteinuria And Left Ventricular Hypertrophy in Hypertensive Patients.

Chillawar, Swapnil; Verma, Anuj; Acharya, Sourya; Kitey, Pritam

doi:10.9790/0853-1602010108

Cited by 1 publication

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References 13 publications

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“…15 Chillawar et al discovered that LVH was associated with microalbuminuria or macroalbuminuria in patients with moderate-to-severe hypertension, following the adjustment for serum creatinine, age, diabetes, race, smoking, hypertension, and other confounding factors. 16 In our study, we also confirmed that increased proteinuria served as a risk indicator for LVH in an independent manner in patients with DKD. Low-density lipoprotein (LDL) is a type of lipoprotein that is involved in transporting cholesterol into the cells of peripheral tissue.…”

Section: Discussionsupporting

confidence: 85%

Risk Factors for Left Ventricular Hypertrophy in Patients with Diabetic Kidney Disease: A Multi-Center Study

Wang¹,

Zhu²,

Peng³

et al. 2023

IJGM

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One of the earliest echocardiographic features of the left ventricle explored extensively was left ventricular hypertrophy (LVH). Numerous studies have identified a few risk factors for LVH, however, there are few for people with diabetic kidney disease (DKD). Therefore, we evaluated the risk factors in DKD patients with LVH by analyzing laboratory data and clinical traits. Methods: In total, 500 DKD patients in the Baoding area from February 2016 and June 2020 were admitted and classified as an experimental group (240 cases, LVH group) and a control group (260 cases, non-LVH group). The clinical parameters and laboratory tests of the participants were collected and analyzed retrospectively. Results: Compared with the control group, low-density lipoprotein (LDL), body mass index (BMI), intact parathyroid hormone (iPTH), systolic blood pressure, and 24-hour urine protein were higher in the experimental group (all P<0.01). Multivariable logistic regression analysis results confirmed that high BMI (OR=1.332, 95% CI 1.016-1.537, P=0.006), LDL (OR=1.279, 95% CI 1.008-1.369, P=0.014) and 24-hour urine proteins (OR=1.446, 95% CI 1.104-1.643, P=0.016) were statistically significant. The ROC analysis illustrated that the optimum cutoff value of BMI, LDL, and 24-hour urine proteins for diagnosis of LVH in patients with DKD was 27.36 kg/m 2 , 4.18 mmol/L, and 1.42 g respectively. Conclusion:The increase in BMI, LDL, and 24-hour urine proteins quantification are independent risk factors for LVH in patients with DKD.

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Section: Discussionsupporting

confidence: 85%

Risk Factors for Left Ventricular Hypertrophy in Patients with Diabetic Kidney Disease: A Multi-Center Study

Wang¹,

Zhu²,

Peng³

et al. 2023

IJGM

View full text Add to dashboard Cite

show abstract

Co-Relation of 24 Hours Proteinuria And Left Ventricular Hypertrophy in Hypertensive Patients.

Abstract: 74±53.71(z -value=3.87,p-value =0.000).Significant positive co-relation was found between proteinuria and LVH(r=0.350,

Cited by 1 publication

References 13 publications

Risk Factors for Left Ventricular Hypertrophy in Patients with Diabetic Kidney Disease: A Multi-Center Study

Risk Factors for Left Ventricular Hypertrophy in Patients with Diabetic Kidney Disease: A Multi-Center Study

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