Co-selection of antibiotic and metal resistance

Baker‐Austin, Craig; Wright, Meredith S.; Stepanauskas, Ramunas; McArthur, J. Vaun

doi:10.1016/j.tim.2006.02.006

Cited by 1,521 publications

(1,025 citation statements)

References 77 publications

Supporting

Mentioning

995

Contrasting

Unclassified

Order By: Relevance

“…Concerning the spread of ARGs in various environments, the effects of co-selection from heavy metals (Baker-Austin et al, 2006), horizontal gene transfer (HGT) (Zhang et al, 2016a), and changes of bacterial community (Udikovic-Kolic et al, 2014) have drawn more and more attention. While high levels of heavy metals existed in sewage sludge, and thus effects of heavy metals on ARGs profiles during sludge treatment should be emphasized.…”

Section: Introductionmentioning

confidence: 99%

Sludge bio-drying: Effective to reduce both antibiotic resistance genes and mobile genetic elements

et al. 2016

View full text Add to dashboard Cite

a b s t r a c tSewage sludge is considered as one of major contributors to the increased environmental burden of ARGs. Sludge bio-drying was increasingly adopted due to its faster sludge reduction compared with composting. The fate of ARGs during full-scale sludge bio-drying was investigated to determine whether it could effectively reduce ARGs, and the contributions of bacterial community, horizontal gene transfer (HGT) through mobile genetic elements (MGEs) and co-selection from heavy metals to ARGs profiles were discussed in detail. Two piles with different aeration strategies (Pile I, the improved and Pile II, the control) were operated to elucidate effects of aeration strategy on ARGs profiles. Results showed that sludge bio-drying could effectively reduce both most of targeted ARGs (0.4e3.1 logs) and MGEs (0.8e3.3 logs) by the improved aeration strategy, which also enhanced both the sludge bio-drying performance and ARGs reduction. The enrichment of ARGs including ermF, tetX and sulII could be well explained by the evolution of bioavailable heavy metals, not HGT through MGEs, and their potential host bacteria mainly existed in Bacteroidetes. Although changes of bacterial community contributed the most to ARGs profiles, HGT through MGEs should be paid more attention especially in the thermophilic stage of sludge bio-drying.

show abstract

Section: Introductionmentioning

confidence: 99%

Sludge bio-drying: Effective to reduce both antibiotic resistance genes and mobile genetic elements

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Similar results was also obtained on isolate 6 that was resistant to 8 antibiotics. The genes encoding resistance to heavy metals can be located together with antibiotic resistance genes on either the same genetic structure or different genetic structures within the same bacterial strain Metal and antibiotic resistances are the most common features that bacteria gain due to the abuse of metals and/or antibiotic [12]. Recent studies have suggested that the presence of metal contamination in natural environments could play a role in the maintenance and proliferation of antibiotic resistance [13,14].…”

Section: Resultsmentioning

confidence: 99%

Heavy metal and antibiotic resistance bacteria in marine sediment of pahang coastal water

Abidin¹,

Chowdhury²

2018

J. CleanWAS

View full text Add to dashboard Cite

The presence of heavy metal and antibiotic resistance bacteria in the marine sediment may indicate heavy metal pollution and antibiotic abuse present in the environment. In this study, a total of 89 bacteria isolated from sediment collected in Teluk Chempedak and Pantai Batu Hitam of Pahang coastal water underwent heavy metal resistance test against Chromium, Cadmium, Nickel, Copper and Cobalt. Previously, these isolates were found to exhibit antibiotic resistance capabilities to at least 5 antibiotics tested. Heavy metal resistance pattern for isolates from Teluk Chempedak was in the form of Cr > Ni >Co >Cd = Cu while for isolates from Pantai Batu Hitam showed a pattern of Cr = Ni >Co >Cu >Cd. Further investigation on the identity of selected isolates that exhibited both antibiotic and heavy metals resistance capabilities using 16S rRNA gene sequences revealed isolates with closest similarities to Staphylococcus saprophyticus and Brevundimonas vesicularis..

show abstract

“…HQ331538), presenting part of a mercury resistance operon and flanked downstream by an IS26 element [7]. This operon (which has been reported to be a conserved region among Salmonella strains) is of great concern, since its co-existence with antibiotic resistance regions suggests indirect selection of antibiotic resistance in S. enterica strains [7,17].…”

Section: Resultsmentioning

confidence: 99%

First description of food-borne Salmonella enterica resistance regions R1 and R3 associated with IS26 elements

Gomes-Neves

Manageiro

Ferreira

et al. 2015

Research in Microbiology

View full text Add to dashboard Cite

In this study, we assessed the presence of IS26 in food-borne ASSuT-type Salmonella enterica isolates. A new genetic region (R3) was described, that included a C14 caspase gene between IS26 elements. R3 was present in two Salmonella Rissen isolates from a swine carcass and a meat handler, collected at the same abattoir. Furthermore, a new rearrangement of resistance region R1, harboring the bla TEM-1 gene flanked by IS26 elements, was identified in Salmonella Typhimurium and Salmonella 4, [5],12:i:-, from different samples. This study highlights the zoonotic potential of Salmonella spp. isolates and the possible role of IS26 in the mobilization of resistance genes.

show abstract

Co-selection of antibiotic and metal resistance

Cited by 1,521 publications

References 77 publications

Sludge bio-drying: Effective to reduce both antibiotic resistance genes and mobile genetic elements

Sludge bio-drying: Effective to reduce both antibiotic resistance genes and mobile genetic elements

Heavy metal and antibiotic resistance bacteria in marine sediment of pahang coastal water

First description of food-borne Salmonella enterica resistance regions R1 and R3 associated with IS26 elements

Contact Info

Product

Resources

About