“…Wound repair is regulated by a number of chemical factors such as cytokines, nitric oxide (NO), and prostaglandins (Chang, Liao, & Kuo, ; Dzik, ; Gonzalez et al, ; Tomlinson & Willoughby, ). Previously we have shown that dysregulation of these mediators contributes to abnormal wound healing causing chronicity of the wound (S. Abd El‐Aleem, Muftah, & Jude, ; Abd El‐Aleem et al, ; Jude, Boulton, Ferguson, & Appleton, ) or excessive fibrosis as in keloid (S. Abd El‐Aleem, Abdelwahab, & Osman, ).…”