CO2 enrichment: Enhancing antioxidant, antibacterial and anticancer activities in Arthrospira platensis

Aydi, Sameh Sassi; Aydi, Samir; Kolsi, Rihab Ben Abdallah; Haddeji, Nouha; Rahmani, Rami; Ktari, Naourez; Bouajila, Jalloul

doi:10.1016/j.fbio.2020.100575

Cited by 16 publications

(6 citation statements)

References 51 publications

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“…This peak was observed under continuous light and repleted nitrogen. Such result converged with Aydi et al, [28] findings stating that carotenoids are synthesized by algae in response to continuous light, nitrate limitation. Furthermore, the hexane crude extracted presenting the highest antioxidant activity was obtained from a biomass collected during the stationary phase (cultured for 10 days) and this phase is characterized by the accumulation of these molecules [29].…”

Section: Discussionsupporting

confidence: 89%

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardiomyoblasts from H2O2-induced oxidative stress

et al. 2022

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Oxidative stress has recently been identified as an important mediator of cardiovascular diseases. The need to find efficient antioxidant molecules is essential in the disease’s prevention. Therefore, the present study aimed to evaluate the potential of microalgae bioactive in protecting H9c2 cardiomyoblasts from H2O2-induced oxidative stress. Four microalgal species were investigated for their antioxidant capacity. A qualitative assessment of oxidative stress in H9c2 cardiomyoblasts stained with DCFH-DA, treated with the highly active microalgae extracts, was performed. The protein expression of total caspase-3 was also examined to investigate whether the extract protects H9c2 cardimyoblasts from H2O2-induced apoptosis. High antioxidant activity was observed for the hexanoic extracts after 10 days of cultivation. Asterarcys quadricellulare exhibited the highest antioxidant capacity of 110.59 ± 1.75 mg TE g−1 dry weight and was tested against H9c2 cardiomyoblasts, which were initially subjected to H2O2-induced oxidative stress. This hexanoic extract protected against H2O2 induced oxidative stress with a similar scavenging capacity as N-Acetylcysteine. Furthermore, total caspase-3 was increased following treatment with the hexanoic extract, suggesting that A. quadricellulare also had anti-apoptotic properties. The outcome of our study highlighted the possible use of the local A. quadricellulare strain QUCCCM10 as a natural, safe, and efficient antioxidant to prevent cardiovascular diseases.

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Section: Discussionsupporting

confidence: 89%

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardiomyoblasts from H2O2-induced oxidative stress

et al. 2022

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show abstract

“…This peak was observed under continuous light and repleted nitrogen. Such result converged with Aydi et al, [27] ndings stating that carotenoids are synthetized by algae in response to continuous light, nitrate limitation. Furthermore, the hexane crude extracted presenting the highest antioxidant activity was obtained from a biomass collected during the stationary phase (cultured for 10 days) and this phase is characterized by the accumulation of these molecules [28].…”

Section: Discussionsupporting

confidence: 88%

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardio-myoblasts from H2O2-induced oxidative stress

Saadaoui

Bounnit

Mraiche

et al. 2022

Preprint

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Oxidative stress is recently identified as an important mediator of cardiovascular diseases. The need to find efficient antioxidant molecules is essential in the disease’s prevention. Therefore, the present study aimed to evaluate the potential of microalgae bioactive in protecting H9c2 cardiomyo-blasts from H2O2-induced oxidative stress. Four microalgal species were investigated for their antiox-idant capacity. A qualitative assessment of oxidative stress in H9c2 cardiomyoblasts stained with DCFH-DA, treated with the highly active microalgae extracts, was performed. The protein expression of total caspase-3 was also examined to investigate whether extract protects H9c2 cardimyoblasts from H2O2-induced apoptosis. High antioxidant activity was observed for the hexanoic extracts after 10 days of cultivation. Asterarcys quadricellulare exhibited the highest antioxidant capacity of 110.59 ± 1.75 mg TE g−1 dry weight and was tested against H9c2 cardiomyoblasts, which were initially subjected to H2O2-induced oxidative stress. This hexanoic extract protected against H2O2 induced oxida-tive stress with a similar scavenging capacity as N-Acetylcysteine. Furthermore, total caspase-3, was increased following treatment with the hexanoic extract, suggesting that A. quadricellulare also had anti-apoptotic properties. The outcome of our study highlighted the possible use of the local A. quadricellulare strain QUCCCM10 as a natural, safe, and efficient antioxidant to prevent cardiovascular diseases.

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“…The highest values of antioxidant activities were obtained in A. platensis (Table 1), mainly in their ethanolic extracts (ABTS •+ = 66.09% ± 2.00 and DPPH = 55.73% ± 0.18). Ismaiel; El-Ayoutu; Piercey-Normore (2016) and Aydi et al, (2020) also showed high antioxidant activity of aqueous extract and methanolic extract from A. platensis, respectively. This activity apparently is associated to the high polyphenols and phycobiliproteins, especially C-phycocyanin, present in A. platensis biomass (AYDI et al, 2020).…”

Section: Antioxidant Activitymentioning

confidence: 90%

“…Ismaiel; El-Ayoutu; Piercey-Normore (2016) and Aydi et al, (2020) also showed high antioxidant activity of aqueous extract and methanolic extract from A. platensis, respectively. This activity apparently is associated to the high polyphenols and phycobiliproteins, especially C-phycocyanin, present in A. platensis biomass (AYDI et al, 2020).…”

Section: Antioxidant Activitymentioning

confidence: 90%

Photosynthetic Microorganisms as Source of Antioxidant and Antibacterial Bioactive Compounds of Interest in the Food Industry

Da Silva,

Moura,

Porto

et al. 2023

REVA

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Bioactive compounds from microalgae and cyanobacteria have been frequently investigated as food preservatives due to their various biotechnological activities. Therefore, this study aimed to evaluate the antimicrobial and antioxidant activities of the aqueous and ethanolic extracts from Dunaliella tertiolecta, Tetradesmus obliquus, and Chlorella vulgaris microalgae and Arthrospira platensis cyanobacteria. The extracts were obtained through the sonication method and the antioxidant activity was determined by ABTS and DPPH methods, whereas antimicrobial activity was evaluated by microdilution assay. In general, ethanolic extracts of all microalgae showed higher antioxidant activity compared to aqueous extracts, especially using ABTS method. All bacteria exhibited higher resistance using the aqueous extracts. Specifically, the gram-negative Pseudomonas aeruginosa was the most susceptible pathogen and was inhibited by all microalgae. The highest antioxidant and antimicrobial activities were obtained by the ethanolic extract from Arthrospira platensis. These data show that ethanolic extract from Arthrospira platensis may be a potential source of antioxidant and antimicrobial compounds with food preservative properties.

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CO2 enrichment: Enhancing antioxidant, antibacterial and anticancer activities in Arthrospira platensis

Cited by 16 publications

References 51 publications

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardiomyoblasts from H2O2-induced oxidative stress

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardiomyoblasts from H2O2-induced oxidative stress

Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardio-myoblasts from H2O2-induced oxidative stress

Photosynthetic Microorganisms as Source of Antioxidant and Antibacterial Bioactive Compounds of Interest in the Food Industry

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