CO2 insufflation during single-balloon enteroscopy: a multicenter randomized controlled trial

Abstract

This study demonstrated an advantage of using CO2 insufflation during single-balloon enteroscopy in patients with a history of previous abdominal surgery. Overall, single-balloon enteroscopy was a well-tolerated procedure that may benefit from the use of CO2 insufflation to reduce post-procedural pain.

Safety of carbon dioxide insufflation during gastric endoscopic submucosal dissection in patients with pulmonary dysfunction under conscious sedation

“…The usefulness and safety of CO 2 as an alternative to air have been demonstrated in several randomized controlled trials for various kinds of endoscopic procedures [20][21][22][23][24], but these studies excluded patients with pulmonary dysfunction because of the possible risk of CO 2 retention and complications. However, many ESD patients are of advanced age, and pulmonary dysfunction prevails in these patients.…”

“…Therefore, CO 2 insufflation is expected to reduce patient pain and abdominal discomfort associated with endoscopic examination and therapy [16][17][18][19][20][21][22]. CO 2 insufflation is also supposed to minimize ESD-related complications such as perforation or vascular injury.…”

Safety of Carbon Dioxide Insufflation during Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma

“…Thus, patient pain and abdominal discomfort associated with endoscopic examinations and therapy can be reduced via the use of CO 2 insufflation [15][16][17][18][19][20][21]. Furthermore, ESD-related complications such as perforation or vascular injury can also be minimized when using CO 2 insufflation.…”

CO2 – ein Muss in der Endoskopie?

“…Auch für die Single-Ballon-Enteroskopie konnten neben einer Schmerzreduktion verbesserte Intubationstiefen gezeigt werden -bei Li et al im Mittel ca. 90 cm von oral und anal[28,29]. In der Studie unserer Arbeitsgruppe zeigte sich die verbesserte Eindringtiefe v. a. bei voroperierten Patienten -im Mittel ca.…”

“…In der Studie unserer Arbeitsgruppe zeigte sich die verbesserte Eindringtiefe v. a. bei voroperierten Patienten -im Mittel ca. 70 cm von oral, sodass der Einsatz von CO 2 gerade in diesem Patientenkollektiv naheliegt[29].CO 2 -Insufflation führt sowohl unter DBE als auch SBE zu weniger Schmerzen und verbesserten Intubationstiefen.…”