Coagulase negative staphylococci

Foster, Timothy J.

doi:10.1016/b978-0-12-818619-0.00016-2

Molecular Medical Microbiology 2024

DOI: 10.1016/b978-0-12-818619-0.00016-2

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Coagulase negative staphylococci

Timothy J. Foster

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2024

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Cited by 3 publications

References 180 publications

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Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

Aniba,

Dihmane,

Raqraq

et al. 2024

Diagnostic Microbiology and Infectious Disease

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Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

Aniba,

Dihmane,

Raqraq

et al. 2024

Diagnostic Microbiology and Infectious Disease

View full text Add to dashboard Cite

A comprehensive review on organ-on-chips as powerful preclinical models to study tissue barriers

Filiz,

Esposito,

De Maria

et al. 2024

Prog. Biomed. Eng.

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In the preclinical stage of drug development, 2D and 3D cell cultures under static conditions followed by animal models are utilized. However, these models are insufficient to recapitulate the complexity of human physiology. With the developing organ-on-chip (OoC) technology in recent years, human physiology and pathophysiology can be modeled better than traditional models. In this review, the need for OoC platforms is discussed and evaluated from both biological and engineering perspectives. The cellular and extracellular matrix components are discussed from a biological perspective, whereas the technical aspects such as the intricate working principles of these systems, the pivotal role played by flow dynamics and sensor integration within OoCs are elucidated from an engineering perspective. Combining these two perspectives, bioengineering applications are critically discussed with a focus on tissue barriers such as blood-brain barrier, ocular barrier, nasal barrier, pulmonary barrier and gastrointestinal barrier, featuring recent examples from the literature. Furthermore, this review offers insights into the practical utility of OoC platforms for modeling tissue barriers, showcasing their potential and drawbacks while providing future projections for innovative technologies.

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Antimicrobial Activities of Extracts of <i>Macrosphyra longistyla</i> against Gram-Positive Oral Biofilm-Formers from School Children in Southwestern Nigeria and Toxicity Studies Using Brine Shrimps

Nwankwo,

Folarin,

Osho

2024

AiM

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The world will benefit from more effective antimicrobial agents against oral conditions arising from the actions of biofilm forming bacteria. Also, information is lacking on the oral biofilm-forming bacterial diversity in Southwestern Nigeria. In this study, we isolate and characterize oral biofilm producing bacteria in the oral cavities of schoolchildren in Southwestern Nigeria.We also investigate the antimicrobial properties of Macrosphyra longistyla extracts against the biofilm-formers and the toxicity of potent extracts. Samples were obtained from 109 schoolchildren aged 4 -14 years from Lagos, Oyo and Osun States. Agar well diffusion technique was used in the antimicrobial susceptibility testing. Toxicity testing was done using brine shrimps (Artemia salina). Biofilm-formers in this study are Klebsiella sp., Streptococcus sp., Staphylococcus sp., and Micrococcus sp. Ethanol leaf extracts had the highest activity against all biofilm-producing bacteria. Ethanol stem bark extract, which elicited activity against Klebsiella only, was found to be less toxic than the ethanol leaf extract. Staphylococcus showed >10 mm susceptibility to the ethanol and aqueous extracts of Macrosphyra longistyla. Streptococcus and Micrococcus were susceptible to the antimicrobial actions of the ethanolic leaf extracts. Although the ethanol extracts of the leaves had lower minimum inhibitory concentrations than the ethanol extracts of the stem bark, toxicity studies showed ethanol extracts of the stem-bark to be more toxic than the ethanol extracts of the leaves. In conclusion, ethanolic extracts of Macrosphyra longistyla show potential as sources of antimicrobials against gram-positive, oral biofilm-forming bacteria.

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Coagulase negative staphylococci

Cited by 3 publications

References 180 publications

Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

A comprehensive review on organ-on-chips as powerful preclinical models to study tissue barriers

Antimicrobial Activities of Extracts of <i>Macrosphyra longistyla</i> against Gram-Positive Oral Biofilm-Formers from School Children in Southwestern Nigeria and Toxicity Studies Using Brine Shrimps

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About

Coagulase negative staphylococci

Cited by 3 publications

References 180 publications

Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

Exploring staphylococcus in urinary tract infections: A systematic review and meta-analysis on the epidemiology, antibiotic resistance and biofilm formation

A comprehensive review on organ-on-chips as powerful preclinical models to study tissue barriers

Antimicrobial Activities of Extracts of &lt;i&gt;Macrosphyra longistyla&lt;/i&gt; against Gram-Positive Oral Biofilm-Formers from School Children in Southwestern Nigeria and Toxicity Studies Using Brine Shrimps

Contact Info

Product

Resources

About

Antimicrobial Activities of Extracts of <i>Macrosphyra longistyla</i> against Gram-Positive Oral Biofilm-Formers from School Children in Southwestern Nigeria and Toxicity Studies Using Brine Shrimps