Coarctation and other obstructive aortic arch anomalies: their relationship to the ductus arteriosus

Elzenga, Nynke J.; Groot, Adriana C. Gittenberger‐de; Oppenheimer-Dekker, Arentje

doi:10.1016/0167-5273(86)90116-6

Cited by 45 publications

(16 citation statements)

References 27 publications

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“…Investigation of biophysical characteristics suggested reduced recoil of the coarcted aortic segment, indicating that the elastic properties of the aortic wall are not preserved [194]. This may be related to cystic medial necrosis [195,196] or to extension of the ductal tissue into the aortic wall [197,198]. However, true cellular pathophysiologic mechanisms responsible for recoarctation have not been clarified.…”

Section: Future Directions Stents In Aortic Coarctationmentioning

confidence: 99%

Transcatheter Stent Therapy in Children: An Update

Sahu

Rao²

2012

Pediat Therapeut

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To address elastic recoil of vessel wall and intimal dissection that can follow balloon angioplasty, stents have been designed and these appear to produce more effective relief of obstruction. Of the two types of stents, namely, balloon expandable and self expandable, balloon expandable stents are most commonly used in children. The usefulness of stents in the management of vascular obstructive lesions not amenable to balloon angioplasty is well established and has been successfully used to treat branch pulmonary artery stenosis, coarctation of the aorta, stenotic right ventricular outflow tract conduits, obstructive lesions of the systemic and pulmonary veins and others. The techniques of implantation, indications, immediate and follow-up results and complications were reviewed. The stents have also been effectively used in keeping open naturally occurring or artificially created inter-circulatory connections and as adjuncts in hybrid procedures, but these have not been discussed in this review. Future directions include investigative work on biodegradable stents and growth stents to address issues related to increase in vessel size in infants and children, use of drug eluding stents to prevent neo-intimal proliferation to avoid pulmonary vein restenosis and refinement of stent technology in hybrid procedures such as neonatal palliation of hypoplastic left heart syndrome and transcatheter completion of Fontan procedure. The feasibility, safety and effectiveness stents in the pediatric population are demonstrated, although scrutiny of results of larger experience with longer follow-up is important.

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Section: Future Directions Stents In Aortic Coarctationmentioning

confidence: 99%

Transcatheter Stent Therapy in Children: An Update

Sahu

Rao²

2012

Pediat Therapeut

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“…A ductal tissue ridge has been demonstrated in the aortic lumen in preductal coarctation of the aorta (CoA) [2,7,9]. With CoLPA the abnormal extension of ductal tissue into the LPA is analogous to that observed in cases of CoA.…”

Section: Discussionmentioning

confidence: 87%

Coarctation of the Left Pulmonary Artery: Effects on the Pulmonary Vasculature of Infants

1997

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At autopsy, two infants had unsuspected coarctation of the left pulmonary artery (CoLPA), which was produced by an extension of ductal tissue into the wall of the left pulmonary artery. The first case, a 4-month-old girl, also had a ventricular septal defect and an anomalous branching pattern of the innominate arterial trunk. Pulmonary arterial hypertensive changes were noted in the right lung. In contrast, the left lung showed thin-walled pulmonary arteries. The second case, a term female newborn, had exhibited severe unexplained respiratory distress since birth. Histologic sections of the right lung showed dilated pulmonary arteries with thinned media, whereas the left lung showed a persistent fetal arterial pattern. It is believed that the peripheral pulmonary arterial changes are age-dependent and associated with asymmetric blood flow between the right and left pulmonary arteries. CoLPA is a rare pulmonary artery defect, and early diagnosis of this abnormality is important.

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“…One animal model showed constriction of the juxtaductal aorta when exposed to high oxygen levels [5]. Support for this theory has also come from clinical studies, with histologic specimens documenting ductal tissue at the coarctation site [3,6,10].…”

Section: Discussionmentioning

confidence: 97%