ITH the recent rapid improvements in methods of diagnosis and treatment of cardiovascular diseases, the surgeon today can attempt to cure the unusual as well as the more common types of defects. Refinements in the technics of cardiac catheterization, angiocardiography, grafting, hypothermia, and extracorporeal circulation have been a great stimulus to the description of the rare lesions in the hope that ultimately a completely corrective procedure can be performed. In this paper, a case of multiple coarctations of the aorta is presented and discussed with a review of the literature. To our knowledge this is the first case report in which there have been 4 distinct coarctations of the aorta.
CASE REPORTThe patient was a 32-year-old Puerto Rican woman with a known murmur since the age of 12 and a recent onset of precordial discomfort, dyspnea, and fatigue. No signs or symptoms of congestive heart failure or subacute bacterial endocarditis were evident. Physical examination revealed the following positive physical findings: the blood pressure was, in the right arm 120/90; in the left arm 205/115, and in the right leg 140/100; the right radial pulse was weak, the left was strong, and the femoral pulses were decreased, but palpable. The heart was enlarged to the anterior axillary line in the sixth intercostal space. A grade-II systolic murmur was heard over the entire precordium, loudest along the left sternal border. No collateral pulsations were felt.Laboratory Findings. The electrocardiogram indicated left ventricular hypertrophy. Radiographic and fluoroscopic examination of the chest showed considerable enlargement of the heart to the left, giving an appearance of left ventricular enlargement. The arch of the aorta showed a shallow impression on its superior posterior aspect and the descending aorta was located unusually far toward the left with the esophagus also somewhat deviated to the left. The configuration of the upFrom the Departments of Surgery and Pathology, The Mount Siniai Hospital, New York, N. Y. 910 per portion of the aorta was somewhat suggestive of the so-called atypical coarctation; however, no narrow segment of aortic arch was visualized, nor was there any evidence of rib notching. Because of the x-ray findings, venous angiocardiography was performed, which revealed a narrowing of the descending aorta in the midthoracic region.Hospital Course. A diagnosis was made of a lower thoracic aortic coaretation with separate occlusion of the right subelavian artery. At surgery, a left thoracotomy revealed a marked stenosis approximately 21/2 inches below the origin of the left subelavian artery. No inflammation or adhesions were observed surrounding the aorta; however, peculiar calcification of the wall of the aorta was noted distal to the coaretation. The aorta was cross clamped above and below the area of coaretation, whereupon the blood pressure rose to over 300 mm. Hg. This blood pressure elevation was controlled with a slow intravenous drip of trimethaphan camphorsulfonate (Arfonad) until the r...