Tourism has a significant role in destination development, particularly in rural regions. However, within the context of the highly sensitive nature of rural areas to the ecological, economic, and socio-cultural effects of tourism development, it is important to assess the levels of satisfaction among the residents of rural destinations. The current study aimed to assess the impact of rural tourism development in the Al-Ahsa region, Saudi Arabia on the overall resident satisfaction and three relevant subdomains. The findings revealed that the three tourism development impacts under investigation, including the social, economic and environmental effects, were positively associated with resident overall satisfaction. The three influential developmental categories were also independent predictors of the satisfaction with the quality of life and environment subdomains. National policy makers are required to implement adequate rural tourism development measures and regulations to improve tourism services and activities, which would eventually be reflected in the quality of life of local residents.