Physical and ecological responses of the coastal areas in the vicinity of Mumbai, India, due to relative sea level rise are examined by different inundation scenarios. Evaluation of potential habitat loss under sea level rise was made by incorporating the land use/land cover (LULC) adopted from the digital elevation model with the satellite imagery. LULC categories overlaid on 1.0, 2.0, 3.0 and 4.0 m coastal elevation showed that the coastal areas of Mumbai were mostly covered by vegetation followed by barren land, agricultural land, urban areas and water bodies. For the relative sea level rise scenarios of 1.0, 2.0, 3.0 and 4.0 m, the tidal inundation areas were estimated to be 257.85, 385.58, 487.56 and 570.63 km 2 , respectively, using GIS techniques. The losses of urban areas were also estimated at 25.32, 41.64, 54.61 and 78.86 km 2 for the 1.0, 2.0, 3.0 and 4.0 m relative sea level rise, respectively, which is most alarming information for the most populated city on the eastern coast of India. The results conclude that relative sea level rise scenario will lead profound impacts on LULC categories as well as on coastal features and landforms in the adjoining part of Mumbai. The sea level rise would also reduce the drainage gradients that promote flooding condition to rainstorms and subsequently increase saltwater intrusion into coastal regions. Alterations in the coastal features and landforms correlated with inundation characteristics that make the coastal region more vulnerable in the coming decades due to huge development activities and population pressures in Mumbai.