Coated and uncoated cellophane as materials for microplates and open-channel microfluidics devices

Hamedi, Mahiar; Ünal, Barış; Kerr, Emily; Glavan, Ana C; Fernández‐Abedul, M. Teresa; Whitesides, George M.

doi:10.1039/c6lc00975a

Cited by 25 publications

(13 citation statements)

References 50 publications

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“…However, LaFratta et al used µTM to fabricate acrylic replicas of masters with overhanging features ( Figure ), by exploiting the deformability of the mold, which allowed mold removal by means of stretching after transfer to a glass substrate. In a method similar to µTM, Hamedi et al used 3D‐printed PU molds to shape paper, which was subsequently assembled to form disposable paper‐based microchannel structures.…”

Section: Fabrication Methods For 3d Structures With Areas Of Various mentioning

confidence: 99%

“…Nanofabrication and microfabrication methods are also used to make nanoelectrochemical and microelectromechanical systems (NEMS and MEMS), for example, for trapping biomolecules or biostructures, for facilitating diagnostic purposes, and for carrying out chemical reactions in a configurable and scalable fashion . MEMS and NEMS can also be paper‐based, making fabricated structures disposable, or fully recyclable at low cost …”

Section: Introductionmentioning

confidence: 99%

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Nanostructure and Microstructure Fabrication: From Desired Properties to Suitable Processes

Assenbergh

Meinders²,

Geraedts

et al. 2018

Small

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When designing a new nanostructure or microstructure, one can follow a processing-based manufacturing pathway, in which the structure properties are defined based on the processing capabilities of the fabrication method at hand. Alternatively, a performance-based pathway can be followed, where the envisioned performance is first defined, and then suitable fabrication methods are sought. To support the latter pathway, fabrication methods are here reviewed based on the geometric and material complexity, resolution, total size, geometric and material diversity, and throughput they can achieve, independently from processing capabilities. Ten groups of fabrication methods are identified and compared in terms of these seven moderators. The highest resolution is obtained with electron beam lithography, with feature sizes below 5 nm. The highest geometric complexity is attained with vat photopolymerization. For high throughput, parallel methods, such as photolithography (≈10 m h ), are needed. This review offers a decision-making tool for identifying which method to use for fabricating a structure with predefined properties.

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Section: Fabrication Methods For 3d Structures With Areas Of Various mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nanostructure and Microstructure Fabrication: From Desired Properties to Suitable Processes

Assenbergh

Meinders²,

Geraedts

et al. 2018

Small

View full text Add to dashboard Cite

show abstract

“…It is primarily used as an environmentally friendly packaging material in food industry. Cellophane can be employed as substrate for the low‐cost and scalable fabrication of disposable sensing devices (even with integrated microfluidics produced by hot embossing). ii) Nanocellulose can be made of cellulose nanofibers, nanocrystalline cellulose, or bacterial nanocellulose.…”

Section: Materials For Disposable Sensorsmentioning

confidence: 99%

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

et al. 2019

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Disposable sensors are low‐cost and easy‐to‐use sensing devices intended for short‐term or rapid single‐point measurements. The growing demand for fast, accessible, and reliable information in a vastly connected world makes disposable sensors increasingly important. The areas of application for such devices are numerous, ranging from pharmaceutical, agricultural, environmental, forensic, and food sciences to wearables and clinical diagnostics, especially in resource‐limited settings. The capabilities of disposable sensors can extend beyond measuring traditional physical quantities (for example, temperature or pressure); they can provide critical chemical and biological information (chemo‐ and biosensors) that can be digitized and made available to users and centralized/decentralized facilities for data storage, remotely. These features could pave the way for new classes of low‐cost systems for health, food, and environmental monitoring that can democratize sensing across the globe. Here, a brief insight into the materials and basics of sensors (methods of transduction, molecular recognition, and amplification) is provided followed by a comprehensive and critical overview of the disposable sensors currently used for medical diagnostics, food, and environmental analysis. Finally, views on how the field of disposable sensing devices will continue its evolution are discussed, including the future trends, challenges, and opportunities.

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“…Microfluidic chip can also be fabricated by other materials, such as metals, [10] cotton, [11] bamboo [12] or cellophane. [13] Even though these materials are not yet broadly applied in immunoassays, they can be of great importance to the whole microfluidic field. Meanwhile, some novel and powerful materials for improving the performance of immunoassay are well developed, such as nanoparticles made of noble metal, quantum dots (QDs), upconversion nanoparticles and membrane-based materials.…”

Section: Methodsmentioning

confidence: 99%

“…[13] These new microfluidic paper-based platforms can achieve many functions using in conventional PDMS channel-based microfluidics. On the one hand, µPADs can be fabricated by a variety of simple but useful printing techniques, such as wax printing, inkjet printing, flexographic printing, screen-printing and wax screen-printing, which make paper as an ideal substrate for POC diagnosis.…”

Section: Papermentioning

confidence: 99%

Materials for Microfluidic Immunoassays: A Review

Mou

Jiang

2017

Adv Healthcare Materials

120

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Conventional immunoassays suffer from at least one of these following limitations: long processing time, high costs, poor user‐friendliness, technical complexity, poor sensitivity and specificity. Microfluidics, a technology characterized by the engineered manipulation of fluids in channels with characteristic lengthscale of tens of micrometers, has shown considerable promise for improving immunoassays that could overcome these limitations in medical diagnostics and biology research. The combination of microfluidics and immunoassay can detect biomarkers with faster assay time, reduced volumes of reagents, lower power requirements, and higher levels of integration and automation compared to traditional approaches. This review focuses on the materials‐related aspects of the recent advances in microfluidics‐based immunoassays for point‐of‐care (POC) diagnostics of biomarkers. We compare the materials for microfluidic chips fabrication in five aspects: fabrication, integration, function, modification and cost, and describe their advantages and drawbacks. In addition, we review materials for modifying antibodies to improve the performance of the reaction of immunoassay. We also review the state of the art in microfluidic immunoassays POC platforms, from the laboratory to routine clinical practice, and also commercial products in the market. Finally, we discuss the current challenges and future developments in microfluidic immunoassays.

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Coated and uncoated cellophane as materials for microplates and open-channel microfluidics devices

Cited by 25 publications

References 50 publications

Nanostructure and Microstructure Fabrication: From Desired Properties to Suitable Processes

Nanostructure and Microstructure Fabrication: From Desired Properties to Suitable Processes

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

Materials for Microfluidic Immunoassays: A Review

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