Coating of silver nanoparticles (AgNPs) on glass fibers by a chemical method as plasmonic surface-enhanced Raman spectroscopy (SERS) sensors to detect molecular vibrations of Doxorubicin (DOX) drug in blood plasma

Functionalized silver nanoparticles for SERS amplification with enhanced reproducibility and for ultrasensitive optical fiber sensing in environmental and biochemical assays

“…† Many studies indicated that the distance between nanoparticles is 2 nm, 43 and the analytical molecules can absorb and fully contact the surface of the nanoparticles. A model using FDTD simulation for coating Ag NPs with a particle diameter of 80 nm and a distance between particles of 60 nm was reported by Vahid Eskandari et al 44 showing the electric field distribution on the surface, and their intensity for application in SERS sensors. Therefore, the 2 hours coating sample has a high uniformity on the surface and less overlap between particles, and it was selected for the highest performance in the sensor.…”

“…Because signal enhancement occurs at the interface of Ag NPs and the analysis molecule when the Ag NPs are overlapped, there is no space le for the analyte molecules to enter the empty slot between Ag NPs due to the limited surface area, and hence, the Raman signal is not enhanced at its best and this is elucidated in Fig S5 . † Many studies indicated that the distance between nanoparticles is 2 nm, 43 and the analytical molecules can absorb and fully contact the surface of the nanoparticles. A model using FDTD simulation for coating Ag NPs with a particle diameter of 80 nm and a distance between particles of 60 nm was reported by Vahid Eskandari et al 44 showing the electric eld distribution on the surface, and their intensity for application in SERS sensors. Therefore, the 2 hours coating sample has a high uniformity on the surface and less overlap between particles, and it was selected for the highest performance in the sensor.…”

Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review

“…Zero-dimensional nanomaterials mostly exist in spherical or quasi-spherical shapes with diameters less than 100 nm [ 47 , 64 ]. The most common 0D materials used in sensing applications are carbon QDs (CQDs) [ 65 , 66 ], semiconductor quantum dots (SQDs) [ 67 , 68 ], graphene quantum dots (GQDs) [ 62 , 69 , 70 , 71 ], CdTe QDs [ 72 , 73 , 74 ], and precious metal NPs such as silver nanoparticles (AgNPs) and AuNPs [ 18 , 20 , 75 , 76 , 77 , 78 ]. However, 0D nanomaterial-based sensing is still in its infancy, and the practical applicability of these nanosensors still has room for advancement, which needs to be solved shortly.…”

“…AgNPs, similar to AuNPs, are noble metal nanoparticles often used in the detection of metabolites and have size-dependent optical, color, and sensing behaviors owing to LSPR [ 61 , 77 , 104 ]. AgNPs are more cost-effective and electrically active and have a higher extinction coefficient.…”

Chitosan-Grafted-Poly(N-vinylcaprolactam)-Decorated Fe3O4@SiO2 Core–Shell Nanoformulation as an Efficient Drug Delivery System for Poorly Soluble Drugs

“…6 Various materials have been explored to enhance the biocompatibility, drug-loading capacity, and targeting specificity of magnetic NPs by modifying their surface functionality. 7 The properties of Fe 3 O 4 nanoparticles enable them to respond to magnetic fields, which enables the targeted administration of drugs to areas within the body. By application of a magnetic field, the Fe 3 O 4 core allows for control over the direction of drug-loaded nanoparticles, enhancing their capacity to gather at the intended therapeutic site.…”