Coatings on Al2O3 by bioactive glass-ceramics

History and trends of bioactive glass‐ceramics

“…Good examples of research to develop bioactive GC coatings on metallic alloy, alumina and zirconia implants were reported by Verné and her co‐workers . Verné et al prepared double‐layer bioactive GC coatings on Ti–6Al–4V substrates by dip coating and firing.…”

Sol–gel derived aluminosilicate coatings on alumina as substrate for osteoblasts

“…Moreover, the trapping of Al into the crystalline phase of high-purity sol-gel aluminosilicate seemed not to affect the osteoblast response on these as dramatically as it does on fluxed glass-ceramics [1,3,9]. In general, for sol-gel glasses, the nanoscale surface topography and porosity provide a high quantity of local partial charges at the peaks [27], which can facilitate the glass matrix dissolution with the formation of Si-OH hydrogel layer thereof, and for glasses with Al, likewise, an aluminosilicate hydrogel film via leaching can be formed [8].…”

“…Although coated titanium implants are most often used, attempts to use coated alumina as an implant for artificial joints have been made. However, on alumina the heat-treatment subjected coatings to Al originating from the substrate, which then diffused into the amorphous glassy phase [1][2][3][4][5]. On biological contact, this cytotoxic Al is leached from the glass-phase, and consequently glass or glass-ceramic compositions that contain even low concentrations of Al, can inhibit the bone interaction [3][4][5][6][7][8].…”

Fabrication and characterization of silk fibroin/chitosan/Nano γ-alumina composite scaffolds for tissue engineering applications

“…[12][13][14][15][16] Chitosan is the N-deacetylated form of chitin obtained by treatment of the latter with a strongly basic solution and is a widely used natural cationic polymer in biomedicine. Porous alumina ceramics has been coated with bioactive coatings such as bioactive glass 24 and calcium phosphate 25 as well as hydroxyapatite. 18,19 Several kinds of bioceramics have been considered for treating damaged and diseased bones with particular emphasis on the bioinert ceramics (e.g.…”