Cobalt complexes of terpyridine ligands: Crystal structure and nuclease activity

On‐Chip Fragment‐Based Approach for Discovery of High‐Affinity Bivalent Inhibitors

“…The lowering in K b value can be accredited to non‐planarity of bipyridines, i.e. phenyl and substituted phenyl at 6‐ and 4‐position respectively 26. The substitution on 6‐positions of one pyridine ring of 2, 2′‐bipyridine is similar to the substitution on either 2‐ or 9‐position of 1, 10‐phenanthroline ligand, which may cause severe steric constraints near the metal core when the complex approaches the DNA base pairs.…”

Different types of copper complexes with the quinolone antimicrobial drugs ofloxacin and norfloxacin: Structure, DNA- and albumin-binding

“…K ox and K red are the binding constants for the binding of the oxidized and reduced forms to DNA. The equilibrium constant (K ox /K red ) [93] for the redox process is found 0.23, 0.27, 0.60 and 0.46 and for 1, 2, 3 and 4, respectively, indicating the stronger DNA binding aptitude of the Cu(II) complexes as compared to complexes containing reduced Cu(I) [95].…”

Interaction studies of cholinium-based ionic liquids with calf thymus DNA: Spectrophotometric and computational methods

“…On the other hand, the non-covalent mode viz. intercalative binding is characterized by hypochromism and bathochromism, whereas electrostatic by comparatively lower hypochromicity without bathochromic shift [46] and groove binding by no or minor change in UV-Vis. spectra.…”