Cobalt(II) and Nickel(II) Complexes of Hydrazone Ligand ({(1E)-1-Aza-2-pyrrol-2-ylvinyl}{5,6-diphenyl(1,2,4-triazin-3-yl)}amine): Synthesis, Spectral, pH Metric, Antimicrobial and PM3 Studies

Samy, Fatma; Ramadan, A. A. T.; Seleem, H.S.; Taha, A.

doi:10.14233/ajchem.2016.20046

Cited by 10 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the light of the above facts, the present work is an extension to our work, covering the synthesis and spectroscopic characterization of triazine‐based ligands . This study explores the coordinating behavior of ( E )‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime towards Fe (III), Cu (I), Ag (I), ZrO ( IV), and UO 2 (VI) ions.…”

Section: Introductionmentioning

confidence: 97%

“…Recently, hydrazones and their metal complexes have attracted extensive attention. This attention comes because of their straightforward synthetic methods and diverse potential applications as, for example, antimicrobial, antitumor, antioxidant, antimalarial, antitubercular, antihypertensive, agents. In addition, hydrazones are employed in catalytic processes, wastewater treatment, and other fields …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis, spectroscopic, biological, and theoretical studies of new complexes from (E)‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime

Samy

2020

Applied Organom Chemis

Self Cite

View full text Add to dashboard Cite

New mononuclear Fe (III), Cu (II), Ag (I), ZrO ( IV) and UO2(VI) complexes were synthesized by the reaction of metal ions with (E)‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime. The structures of the metal complexes were characterized using analytical, spectral (infrared, electronic, 1H NMR, electron spin resonance (ESR), and mass), magnetic moment, molar conductance, thermal gravimetric analysis, and powder X‐ray diffraction (XRD) measurements. All complexes have octahedral geometries except the Cu (II) complex, which has square planar geometry, and the UO2(VI) complex, in which the coordination number is seven. The ligand acts as a (neutral, monoanionic or dianionic) tridentate with N2O coordinating sites: N‐azomethine, N‐triazine, and O‐oxime. Fluorescence spectral studies were carried out in solid state and in dimethylformamide (DMF). The kinetic parameters of the thermal decomposition stages were calculated using Coats–Redfern equations. The morphological structures of the ligand and some complexes were determined using XRD. The molecular orbital calculations were carried out for the ligand and metal complexes using the Hyperchem 7.52 program on the basis of the PM3 level. The antimicrobial activities of the ligand and its complexes were investigated towards the microorganisms S. aureus and B. subtilis as Gram‐positive bacteria, S. typhimurium and E. coli as Gram‐negative bacteria, C. albicans, and A. fumigatus. The ligand and its complexes showed antitumor activity against Hep G‐2 cell lines, where Cu (II) and Ag (I) complexes seem to be promising as they showed IC50 values that are lower than and comparable to that of the antitumor drug doxorubicin.

show abstract

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Synthesis, spectroscopic, biological, and theoretical studies of new complexes from (E)‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime

Samy

2020

Applied Organom Chemis

Self Cite

View full text Add to dashboard Cite

show abstract

“…The IR spectra of the hydrazones (AHQ & BHQ) (Table 1) showed very strong bands at ca. 1616 -1614 and 3440 -3175 cm -1 which are attributed to ν(C=N) and ν(NH), respectively [25][26][27][28][29][30][31][32][33][34]. On the other hand, the broad band centered at 2868 cm -1 is assignable to ν(OH---N) of the phenolic group of AHQ, ligand [35][36][37].…”

Section: Ir and Mass Spectra Of The Ligandsmentioning

confidence: 99%

“…On the basis of the high molar absorptivity ε max , the highest energy bands at λ 1 (239 -247 nm) are assigned to π -π* transitions of the quinoline ring [7], phenyl rings and/or azomethine groups. Also, the moderate energy bands at λ 2 (344 -351 nm) may be composite bands due to charge transfer (CT) interactions [25][26][27][28][29]. Finally, the lower energy bands at λ 3 (329 -418 nm) can be ascribed to the low intensity n -π* forbidden transitions.…”

Section: Electronic Spectra Of the Ligandsmentioning

confidence: 99%

pH-metric and theoretical studies of the complexation of 2-[α-(o-hydroxyphenyl) ethylidenehydrazino]-4,6-dimethylquinoline and 2-[α-(o-methoxyphenyl)methylidenehydrazino]-4,6-dimethylquinoline

et al. 2018

Self Cite

View full text Add to dashboard Cite

2-[α-(o-Hydroxyphenyl)ethylidenehydrazino]-4,6-dimethylquinoline (AHQ) and 2-[α-(omethoxyphenyl)methylidenehydrazino]-4,6-dimethylquinoline (BHQ) have been synthesized and characterization is performed by elemental analysis and electronic, vibrational and mass spectra. The pK H and log K were gritty in 75% solvent-water pH-metrically for BHQ ligand and at various temperatures for AHQ ligand. The dissociation and stability constants in the aqueous medium for BHQ ligand have been calculated by the relation of pK H or log K with solvent parameters (D, ET, AN and DN). The isokinetic temperature was determined by using a linear regression analysis (LRA) of ΔΗ° vs. ΔS° for AHQ complexes. The thermodynamic parameters of AHQ compounds were analyzed into their electrostatic (el) and non-electrostatic (non) or cratic components. Full geometrical and structural optimizations of the ligands have been performed by a DFT study by using the hyperchem program.

show abstract

“…Pyrrole is important heterocyclic compound, where porphyrins (haem), chlorines (chlorophyll) and corrin (vitamin B12) contain pyrrole ring [36]. This is extension to work on the ligand, (2-pyrrole)-(5,6diphenyl- [1,2,4]-triazin-3-yl)hydrazone, HPT, where in our previous studies, the binary and ternary complexes of Ni(II) and Co(II) complexes were isolated and characterized [37]. On the other hand, the pH-metric studies of the free ligand, Ni(II) and Co(II) ions have been discussed in our previous study [37].…”

Section: Introductionmentioning

confidence: 99%

pH-Metric studies of (2-pyrrole)-(5,6-diphenyl-[1,2,4]-triazin-3-yl)hydrazone with inner transition metals

et al. 2020

Self Cite

View full text Add to dashboard Cite

The reaction of (2-pyrrole)-(5,6-diphenyl-[1,2,4]-triazin-3-yl)hydrazone with trivalent 4f lanthanide metal ions (La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III), Ho(III), Er(III) and Yb(III)) and 5f actinide metal ion UO 2 (II) has been studied potentiometrically in 75% (v/v) dioxane-water; at 283, 293, 303 and 313K. The ligand behaves as mono-protic species with the dissociation of hydrazo group proton and reacts with metal ion in molar ratio 1:2; M:L in solution. The formation constants were caulculated, which decrease as temprerature increases. The negative values of ΔH  and ΔG° indicate that the complexation process is exothermic and proceeds spontaneously, respectivily. The electrostatic forces are weaker than non-electrostatic forces, where-G°n on is lower than-G°e l. G°e l has negative comparable values and suggests that the complexation process is affected by the temperature and environment. The higher negative value of H  1non than H  2non for UO 2-complex would reflect that the bond strength from ligand to UO 2 ion, which is stronger in the 1 st coordination than the 2 nd coordination.

show abstract

Cobalt(II) and Nickel(II) Complexes of Hydrazone Ligand ({(1E)-1-Aza-2-pyrrol-2-ylvinyl}{5,6-diphenyl(1,2,4-triazin-3-yl)}amine): Synthesis, Spectral, pH Metric, Antimicrobial and PM3 Studies

Cited by 10 publications

References 0 publications

Synthesis, spectroscopic, biological, and theoretical studies of new complexes from (E)‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime

Synthesis, spectroscopic, biological, and theoretical studies of new complexes from (E)‐3‐(2‐(5, 6‐ diphenyl‐1,2,4‐ triazin‐3‐ yl)hydrazono)butan‐2‐ one oxime

pH-metric and theoretical studies of the complexation of 2-[α-(o-hydroxyphenyl) ethylidenehydrazino]-4,6-dimethylquinoline and 2-[α-(o-methoxyphenyl)methylidenehydrazino]-4,6-dimethylquinoline

pH-Metric studies of (2-pyrrole)-(5,6-diphenyl-[1,2,4]-triazin-3-yl)hydrazone with inner transition metals

Contact Info

Product

Resources

About