“…[3] Very recently, Reiser et al reported that the azabis(oxazoline) is a superior ligand for cobalt-catalyzed ACR of esters and carboxamides. [4] On the other hand, as for copper catalysts, chiral copper-hydride species generated by reaction of CuCl/NaOtBu/TolBINAP and PMHS (PMHS = polymethylhydrosiloxane) was reported by Buchwald et al in 1999 to show higher enantioselectivity for esters, and the system was then applied to ACR giving optically active cyclopentanones, lactones, lactams, and b-azaheterocyclic acid derivatives. [5] Around the same time, Lipshutz et al also reported that copper catalysts bearing chiral bisphosphine, JOSIAbstract: New asymmetric conjugate reduction of b,b-disubstituted a,b-unsaturated ketones and esters was accomplished with alkoxylhydrosilanes in the presence of chiral rhodium(2,6-bisoxazolinylphenyl) complexes in high yields and high enantioselectivity.…”