Coberturas vacinais e doenças imunopreveníveis no Brasil no período 1982-2012: avanços e desafios do Programa Nacional de Imunizações

Prevalência e fatores associados à ocorrência de eventos adversos pós-vacinação em crianças

“…(19) In this study, HHE were the most prevalent event, and other severe and unusual events associated with the tetravalent and pentavalent vaccines were registered. Studies conducted in Teresina and Campo Grande verified HHE as the second and fourth (8,15) most prevalent event, and fever > 39.5º, pain, flushing, and heat as the most prevalent events.…”

“…(1,14) The high frequency of AEFI in children under one year old found in this study was also evidenced in other studies. (7,8,15) This study points out that in this age group there is a higher concentration of vaccines applied and the immune system is still immature, increasing the probability of infectious processes, allergies, and clinical alterations that may be associated with immunization. (13,14,16,17) The present study evidenced the predominance of AEFI in children aged between 3 and 6 months.…”

“…A study conducted in Uruguay (16) found a higher frequency for males between 2 months and 17 years old, and a study conducted in Brazil evidenced a predominance of female children. (15) Tetravalent and pentavalent vaccines presented the highest frequency of AEFI. Other studies associated AEFI with DTP (15) and BCG.…”

“…(15) Tetravalent and pentavalent vaccines presented the highest frequency of AEFI. Other studies associated AEFI with DTP (15) and BCG. (8) The tetravalent vaccine was implemented in the routine of immunization of the Unified Health System in 2002 and the pentavalent vaccine in 2012.…”

Panorama da cobertura vacinal brasileira com enfoque no município de Jataí, Goiás entre 2011 e 2015

“…2 De acordo com a Coordenação-Geral do Programa Nacional de Imunizações (CGPNI) em 2013, foram ofertados ao todo 44 produtos entre vacinas, soros e imunobiológicos, destes 15 eram vacinas dos calendários de vacinação como demosntrado no quadro 1. 1,[3][4][5][6] O PNI tem se tornado referência em outros países, onde tem auxiliado na organização de campanhas de vacinação, programas de imunização e ações de cooperação técnica. 7 Entre os países emergentes é considerado o programa mais efetivo de vacinação, e é comparado aos programas de vacinação dos países desenvolvidos.…”