Cocaine enhances figural, but impairs verbal ‘flexible’ divergent thinking

Hutten, Nadia R. P. W.; Steenbergen, Laura; Colzato, Lorenza S.; Theunissen, Eef L.; Ramaekers, Johannes G.; Kuypers, Kim P.C.

doi:10.1016/j.euroneuro.2019.06.003

Cited by 6 publications

(2 citation statements)

References 54 publications

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“…The results of the current study on MCUD were in line with researches on other SUDs. Previous research utilizing a similar task, Tower of London task (recognized as an equivalent assessment of planning or problem-solving ability as TOH), indicated that taking 300 mg of cocaine orally could result in the reduction of thinking flexibility in the TOL task (Hutten et al 2019). Also, cocaine-dependent patients had significant dysfunction of problem-solving ability as well, making more mistakes and spending longer time to complete the task (Inozemtseva et al 2016).…”

Section: Discussionmentioning

confidence: 99%

Problem-solving deficits in methcathinone use disorder

et al. 2021

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Rationale The use of methcathinone (MCAT), a psychostimulant drug that can lead to long-term health risks and executive dysfunction, increased to an alarming rate in recent years. Impairments in low-level executive function have been reported in substance use disorder. However, little empirical evidence is available regarding high-level executive function (e.g., problem solving), which may act as a risk factor for relapse. Objectives The present study aimed to investigate whether the problem-solving ability was altered in abstinent individuals with methcathinone use disorder (MCUD). Here, we tested fifty male MCUD individuals (short-term MCUD group: twentynine patients with MCAT use less than 3 years, long-term MCUD group: twenty-one patients with MCAT use longer than 3 years, which were split by medium years of drug use) and twenty-four well-matched healthy controls (HC) in the Tower of Hanoi task (TOH) to assess the impact of task difficulty on drug-related changes in problem-solving performance. We used several measures to characterize problem-solving performance: the number of mistakes made, the completion time of the task, and the thinking time before the first move. ResultsIn the low task difficulty condition, the MCUD group and HC group showed similar levels of mistakes and completion time, while in the high task difficulty condition, the MCUD group reported more mistakes (the mean number of mistakes in each trial: 1.41 ± 1.15 vs 0.79 ± 0.76, P = 0.019, Cohen's d = 0.635) and longer completion time in the task (the mean completion time in each trial: 45.83 ± 20.51 s vs 33.40 ± 15.10 s, P = 0.010, Cohen's d = 0.690) than the HC group. The thinking time before the first move did not differ significantly between groups (P = 0.257). We further found that the long-term (more than 3 years) MCUD group made more mistakes than the short-term MCUD group and HC group, mainly in the highly difficult subtasks. The longer time than HCs was reported in the long-term MCUD group among high task difficulty of subtasks. In addition, there was a positive correlation between years of MCAT use and the number of mistakes made in high task difficulty TOH task (r = 0.326, P = 0.021). Conclusions Chronic methcathinone use was associated with deficits in problem-solving performance, which depended on the degree of task difficulty. The impairment was more evident in the long-term (> 3 years) MCAT group.

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Section: Discussionmentioning

confidence: 99%

Problem-solving deficits in methcathinone use disorder

et al. 2021

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“…Five studies investigated the influence of certain experimental interventions on creative thinking, such as e-learning (Hong et al, 2019;Huang, 2019) and mindfulness (Strick et al, 2012;Kim, 2015;Colzato et al, 2017). In addition, some studies explored how drug (Ding et al, 2015;Mohamed, 2016;Hutten et al, 2019) and alcohol use (Jarosz et al, 2012;Benedek et al, 2017) influence creative thinking, and whether music (Eskine et al, 2018;Threadgold et al, 2019), eye movements (Fleck and Braun, 2015), and outdoor sports (Ferraro, 2015) promote creative performance. Generally, the aforementioned studies focused on the effects of external manipulation and interventions on creative thinking.…”

Section: Effect Of Treatmentmentioning

confidence: 99%

A Systematic Review of Creativity-Related Studies Applying the Remote Associates Test From 2000 to 2019

Huang

Chen

et al. 2020

Front. Psychol.

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The study examines how the remote associates test (RAT) has been used to examine theories of creativity through a review of recent studies on creativity. Creativity-related studies published between 2000 and 2019 were retrieved from the SCOPUS database. A total of 172 papers were chosen for further analysis. Content analysis shows that research on creativity using RAT mainly concerns remote association, insight problem-solving, general creative process, test development, individual difference, effect of treatment, clinical case, social interaction effect, and predictor or criterion. The study constructs a theoretical framework based on the 4P (Product-Person-Process-Place) model and demonstrates how empirical studies using the RAT explore the individual differences, internal processes, and external influences of creative thinking. In addition, the most commonly used version of the RAT is the Compound Remote Associates Problems (Bowden and Jung-Beeman, 2003a). Current research shows a trend whereby the creative thinking process has been receiving greater attention. In particular, a growing number of studies in this field have been carried out using cognitive neuroscience technologies. These findings suggest that the RAT provides researchers with a way to deepen their understanding of different levels of creativity.

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