Coccidioidomycosis Update and Review

Schneider, Daniel

doi:10.1007/s40138-023-00274-3

Cited by 1 publication

(3 citation statements)

References 54 publications

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“… This map of Mexico and the Southwestern United States shows where infections are supposed to have been acquired. It is color-coded to differentiate between known or not known to be endemic regions [ 14 ]. …”

Section: Figurementioning

confidence: 99%

“…In practice, however, most diagnoses of this infection are made based on positive serologies. As is true for many infections, ELISA results may be falsely positive for IgM due to rheumatoid factors or non-specific IgM, but a positive IgG indicates infection [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…The incubation period ranges from 7 to 21 days. Disseminated coccidioidomycosis (DCM) is most common in individuals with immunosuppression [ 15 ], pregnant women, and those more than 65 years old; increased risk has also been inferred among those who identify as African–American or Filipino [ 14 , 16 ]. The skin, lymph nodes, musculoskeletal system, and central nervous system (CNS) are the most common dissemination sites, occurring in less than 1% of cases [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Coccidioidomycosis in Immunocompromised at a Non-Endemic Referral Center in Mexico

Román-Montes,

Seoane-Hernández,

Flores-Miranda

et al. 2024

JoF

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The incidence and distribution of coccidioidomycosis are increasing. Information scarcity is evident in Mexico, particularly in non-endemic zones and specific populations. We compared the treatment and outcomes for patients with isolated pulmonary infections and those with disseminated coccidioidomycosis, including mortality rates within six weeks of diagnosis. Of 31 CM cases, 71% were male and 55% were disseminated. For 42% of patients, there was no evidence of having lived in or visited an endemic region. All patients had at least one comorbidity, and 58% had pharmacologic immunosuppressants. The general mortality rate was 30%; without differences between disseminated and localized disease. In our research, we describe a CM with a high frequency of disseminated disease without specific risk factors and non-significant mortality. Exposure to endemic regions was not found in a considerable number of subjects. We consider diverse reasons for why this may be, such as climate change or migration.

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Section: Figurementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%