We acknowledge with sincere thanks numerous discussions with Dr Rebecca J. Moore during the preparation of this and other manuscripts. Despite the many improvements resulting from these discussions, the opinions expressed here are those of the listed authors and are not necessarily shared by their advisors.Author Contributions: D.M. was responsible for original draft preparation, M.H. and D.M for review and editing. All authors contributed to the text equally according to their topic specialties. All authors have read and agreed to the published version of the manuscript; supervision and project administration, D.M.