Cochlear and Vestibular Functional Study in Patients with Sudden Deafness and Lyme Disease

Selmani, Ziane; Pyykkö, Ilmari

doi:10.4236/ijohns.2014.31010

Cited by 7 publications

(7 citation statements)

References 15 publications

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“…One of the most peculiar features of neuroborreliosis can manifest up to 1 year after a disseminated infection, as in this case report 2 . It is assumed that the pathogenetic mechanism of the SSNHL in Lyme disease is related both to an immunological reaction and to an angiopathic injury of the cochlea 17,21,22 . On the contrary, facial nerve involvement seems to be related only to an aspecific inflammatory process 19,23 .…”

Section: Discussionmentioning

confidence: 69%

“…2 It is assumed that the pathogenetic mechanism of the SSNHL in Lyme disease is related both to an immunological reaction and to an angiopathic injury of the cochlea. 17,21,22 On the contrary, facial nerve involvement seems to be related only to an aspecific inflammatory process. 19,23 According to the current literature, the diagnosis of neuroborreliosis requires meeting the following criteria: neurologic signs compatible with Lyme neuroborreliosis, CSF pleocytosis (>5 cells × 10 9 L), intrathecal production of specific antibodies (B. burgdoferi IgM and/or IgG).…”

Section: Discussionmentioning

confidence: 99%

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Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy

Nitro

Martino

Fuccillo

et al. 2022

Clinical Case Reports

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We present a case of sudden sensorineural hearing loss and rapidly progressive facial palsy in a female patient in her 40s with no, apparently, notable past medical or surgical history. Investigations revealed a positive serology for B. burgdoferi and the MRI allowed us to identify suggestive signs of Lyme meningitis with multiple cranial nerve involvement. After diagnosis, the patient was treated with intravenous ceftriaxone with a full recovery of sensorineural deafness and facial palsy. This case report highlights the importance of collecting a complete medical history in all cases of facial palsy and sudden hearing loss while presenting an infrequent clinical presentation of early disseminated Lyme disease with neuroborreliosis.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy

Nitro

Martino

Fuccillo

et al. 2022

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…Very often, the symptoms coincided with hearing loss and tinnitus, which implies the location of the disease being within the inner ear. Selmani et al [18] confirmed the occurrence of vertigo in five out of eight patients with LD (62.5%), comparing the results with a group of patients with idiopathic sudden deafness. Ishizaki et al [19] suggest that vertigo can be the predominant symptom in patients with confirmed LD, its symptoms resembling neuronitis vestibularis in the acute stage.…”

Section: Discussionmentioning

confidence: 83%

Vertigo as One of the Symptoms of Lyme Disease

Sowula

Szaleniec

Dworak

et al. 2021

JCM

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Objectives: The aim of the study was to evaluate the frequency of vertigo symptoms and potential labyrinth damage in patients with diagnosed Lyme disease (LD). LD can affect the vestibulocochlear nerve, leading to hearing loss and vertigo/dizziness. Material and Methods: The study included a group of 38 patients between the ages of 20 and 77, who were hospitalized due to vertigo/dizziness between 2018 and 2019. All of the patients underwent a detailed medical interview and an otolaryngological and neurological examination, including video electronystagmography (VENG), in addition to audiological and diagnostic tests. Additionally, ELISA and Western blot tests were performed to confirm the diagnosis of LD. Results: In 20 patients (53%), the Romberg trial was positive (p < 0.001). The degree of vestibular dysfunction as shown by the VENG test was associated with the rate of hearing loss as confirmed by the Auditory Brainstem Response (ABR) test (p = 0.011), and it mainly concerned high-frequency sounds (p = 0.014). Conclusion: Vertigo can be a symptom of LD. It is often associated with labyrinth and hearing-organ damage, which can imply that the inner ear or nerve VIII is dysfunctional in the course of this disease. Antibiotic therapy is effective in reducing otoneurological symptoms.

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“…On the other hand, Selmani et al suggest that hearing loss in LD could be a result of inflammation impact by an immunological reaction in the cochlea by BB infection. The first manifestation of this reaction is an elevated level of IgM [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…Otolaryngological manifestation of LD included different symptoms such as sore throat, otalgia, cervical adenopathy, facial nerve palsy tinnitus, vertigo, and hearing loss. Many authors have been mentioned the occurrence of hearing loss in LD patients [ 3 , 9 , 10 , 11 ], but only a few reports in the literature concern sudden loss of hearing cases [ 9 , 12 , 13 , 14 ]. The aim of the study was to assess the prevalence of SSNHL among the hospitalized patients; furthermore, it includes an attempt to answer the question of whether the Borrelia burgdorferi infection that causes Lyme disease may be the reason for SSNHL.…”

Section: Introductionmentioning

confidence: 99%

Association between Sudden Sensorineural Hearing Loss and Lyme Disease

Sowula

Szaleniec

Stolcman

et al. 2021

JCM

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Objectives: Sudden sensorineural hearing loss (SSNHL) is defined as sensorineural hearing loss of 30 dB or more over at least three adjacent audiometric frequencies occurring within a 72-h period of time. One of the causes of SSNHL could be the progressive inflammatory state caused by an infection. The aim of this study was to assess the prevalence of SSNHL caused by various factors, most importantly those potentially related to Lyme disease. Material and Methods: The study includes a group of 86 patients between the ages of 20 and 70 who were hospitalized due to SSNHL between 2017 and 2018. All of these patients underwent a detailed medical interview and an otolaryngological examination, including audiological and diagnostic tests. Additionally, ELISA and Western blot tests were performed to confirm the diagnosis of Lyme disease. Results: In this group of 86 patients, nine patients presented with positive antibodies toward Borrelia burgdorferi sensu lato. This group was treated with antibiotics and experienced partial or complete regression of their deafness. This may suggest a relationship between SSNHL and Lyme disease. Conclusion: Infections caused by Borrelia burgdorferi may contribute to the development of inflammatory and angiopathic lesions, which are a possible cause of SSNHL. The longer the duration of the infection, the greater the likelihood of permanent and irreversible changes in the vessels of the cochlea or auditory nerve. Therefore, serological tests for Borrelia burgdorferi should be performed during the diagnosis of SSNHL as a possible cause of this illness.

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Cochlear and Vestibular Functional Study in Patients with Sudden Deafness and Lyme Disease

Cited by 7 publications

References 15 publications

Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy

Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy

Vertigo as One of the Symptoms of Lyme Disease

Association between Sudden Sensorineural Hearing Loss and Lyme Disease

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