Cochlear sequestrum — An uncommon complication of a common disease

Prasannaraj, M S Thomas; De, Narajit S.; Narasimhan, Indira

doi:10.1007/bf03050780

Cited by 4 publications

(5 citation statements)

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“…The treatment of OL described in the existing literature involves aggressive debridement to inhibit inflammation and infection (1,2,5,6). This includes empiric or culture-directed antibiotic therapy, surgical exploration with partial or complete labyrinthectomy, and debridement of surrounding involved tissue to prevent further recurrence or progression of disease in infectious cases (1,2).…”

Section: Discussionmentioning

confidence: 99%

“…OL is a rare disease with less than 10 reported cases in the literature (1)(2)(3)(4)(5)(6). Previously, the term labyrinthine sequestrum was most commonly used to describe this erosive labyrinthine process, as most cases demonstrated bony sequestrum within the otic capsule (1)(2)(3)(4)(5)(6).…”

Section: Discussionmentioning

confidence: 99%

“…OL is a rare disease with less than 10 reported cases in the literature (1–6). Previously, the term labyrinthine sequestrum was most commonly used to describe this erosive labyrinthine process, as most cases demonstrated bony sequestrum within the otic capsule (1–6).…”

Section: Discussionmentioning

confidence: 99%

“…Osteolytic labyrinthitis (OL) is a rare sequela of labyrinthitis characterized by obliteration of the bony and membranous labyrinth, with potential formation of sequestrum as a late finding (1)(2)(3)(4)(5)(6). OL is distinct from membranous labyrinthitis, which may result in labyrinthitis ossificans in more severe cases.…”

Section: Introductionmentioning

confidence: 99%

“…The existing literature on OL is extremely limited with less than 10 case reports to date. All reported cases were seen in patients suffering from chronic suppurative otitis media (CSOM) (1)(2)(3)5,6). The exact etiopathogenesis remains unknown, but this pattern suggests a chronic process, most commonly with a bacterial infectious etiology.…”

Section: Introductionmentioning

confidence: 99%

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Cochlear Implantation in Patients With Osteolytic Labyrinthitis: A Case Series

Thedinger,

Dornhoffer,

Merlino

et al. 2024

Otol Neurotol

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Objective To describe the rare process of osteolytic labyrinthitis, previously referred to as labyrinthine sequestrum, which involves progressive obliteration of the bony and membranous labyrinth with eventual supplantation with soft tissue and, in some cases, bony sequestrum. Patients Three patients with diverse presentations of osteolytic labyrinthitis from two tertiary care academic medical centers. Intervention(s) Case series report analyzing the relevant clinical, radiologic, pathologic, and surgical data on our patients with osteolytic labyrinthitis and comparing these index cases to the existing literature. Main Outcome Measure(s) We describe the varying image findings seen in osteolytic labyrinthitis on computed tomography and magnetic resonance imaging. Also, we report successful surgical intervention and hearing rehabilitation with cochlear implantation in patients with osteolytic labyrinthitis. Results Our three patients presented with profound sudden sensorineural hearing loss and vertigo consistent with labyrinthitis. None of the three patients had a history of chronic otitis media. Imaging workup revealed varying degrees of erosion to the otic capsule bone demonstrating the spectrum of disease seen in osteolytic labyrinthitis. Although two cases showed osteolytic changes to the semicircular canals and vestibule, the first case revealed frank bony sequestrum within the obliterated labyrinth. The three cases were taken for surgical debridement and cochlear implantation. Conclusions We propose the new term, osteolytic labyrinthitis—previously referred to as labyrinthine sequestrum—to describe the rare spectrum of disease characterized by destruction of the osseous and membranous labyrinth and potential supplantation with bony sequestrum. Cochlear implantation is a viable option in selected patients with osteolytic labyrinthitis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cochlear Implantation in Patients With Osteolytic Labyrinthitis: A Case Series

Thedinger,

Dornhoffer,

Merlino

et al. 2024

Otol Neurotol

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Labyrinthine sequestration secondary to auditory implantation: report of two cases and review of the literature

et al. 2015

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To the authors' knowledge, these are the first reported cases where vestibular sequestration has resulted from auditory implant surgery. This paper outlines the radiological changes characteristic of this pathology. It also describes the surgical and conservative treatment options for this condition, challenging the previously accepted belief that affected patients always require aggressive surgical intervention.

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