Coconut (Cocos nucifera L.) Lipids: Extraction and Characterization

Hudiyanti, Dwi; Khafiz, Muhammad Fuad Al; Anam, Khairul

doi:10.13005/ojc/340268

Cited by 7 publications

(4 citation statements)

References 27 publications

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“…The fatty acid chain residues found in CocoPCs, which have a peak area of more than 10%, is presented in Table 1. The results confirm similarity between the fatty acid residues found in CocoPCs with the one in coconut lipids 10 . Characterization of CocoPCs, using LC-MS with positive ion mode, resulted in the chromatogram shown in Fig .…”

Section: Isolation Of Cocopcssupporting

confidence: 81%

“…Isolation of CocoPLs from dried coconut powder was performed according to the method presented by Hudiyanti et al, 10,11 . Briefly, the technique was as follows: dried coconut powder was macerated with a chloroform and methanol mixture (2: 1 v/v).…”

Section: Isolation Of (Cocopls)mentioning

confidence: 99%

“…Research by Hudiyanti et al, 10 used methanol eluent in coconut crude lipids to obtain Coconut phospholipids (CocoPLs). Coconut phospholipids contain phosphatidylcholine (CocoPCs), phosphatidylserine (cocoPSs), and/or phosphatidylethanolamine (cocoPEs) species with the lipophilic groups of dodecanoic acid (C12:0), octadecanoic acid (C18:0) and hexadecanoic acid (C16:0), which are abundant in CocoPLs 3 .…”

Section: Introductionmentioning

confidence: 99%

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A Study of Coconut (Cocos Nucifera L.) Phosphatidylcholine Species

et al. 2018

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Coconut (Cocos nucifera L.) phosphatidylcholines, or CocoPCs species are studied in this paper. CocoPCs is fractionated from coconut phospholipids (CocoPLs) using methanol eluent in silica column chromatography. Analysis of the CocoPCs, by FTIR, GCMS and LCMS, reveals that among the isolated CocoPCs species are 16:0/18:0-PC with m/z 763 at Rf 6.02 and 18:1-LysoPC with m/z 522 at Rf 4.93. The composition of CocoPCs fatty acid chain residues are Dodecanoic acid (C12:0), Tetradecanoic acid (C14:0), 9-Hexadecenoic acid (C16:1), Hexadecanoic acid (C16:0), 9,12-Octadecadienoic acid (Z,Z) (C18:2), 9-Octadecenoic acid (C18:1) and Octadecanoic acid (C18:0). The CocoPCs content is 6.317% of 100 mg CocoPLs.

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Section: Isolation Of Cocopcssupporting

confidence: 81%

Section: Isolation Of (Cocopls)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Study of Coconut (Cocos Nucifera L.) Phosphatidylcholine Species

et al. 2018

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“…The CocoPLs were extracted in-house using the method outlined by [30,31]. In brief, the CocoPLs were extracted from ripe coconut meat using a chloroform (Merck KgaA, Darmstadt, Germany) p.a.…”

Section: Encapsulation Of Curcumin In Cocoliposomes With Gum Arabic M...mentioning

confidence: 99%

Prospect of Gum Arabic–Cocoliposome Matrix to Encapsulate Curcumin for Oral Administration

Hudiyanti,

Al Khafiz,

Anam

et al. 2024

Polymers

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Curcumin is an antioxidant that can effectively eliminate free radicals. However, as its oral bioavailability is low, an effective delivery method is required. Phospholipid-based liposomes can encapsulate lipophilic drugs, such as curcumin, while liposome, cholesterol, and gum Arabic (GA) can enhance the internal and external stability of drug membranes. This present study used concentrations of cholesterol (Cchol) and GA (CGA), ranging from 0 to 10, 20, 30, and 40% as well as 0 to 5, 10, 15, 20, 30, and 40%, respectively, to encapsulate curcumin in a GA–cocoliposome (CCL/GA) matrix and test its efficacy in simulated intestinal fluid (SIF) and simulated gastric fluid (SGF). The absence of new characteristic peaks in the Fourier transform infrared (FTIR) spectra results indicate the presence of non-covalent interactions in the CCL/GA encapsulation. Furthermore, increasing the Cchol decreased the encapsulation efficiency (EE), loading capacity (LC), and antioxidant activity (IR) of the CCL/GA encapsulation but increased its release rate (RR). Conversely, increasing CGA increased its EE and IR but decreased its LC and RR. The two conditions applied confirmed this. Liposomal curcumin had the highest IR in SIF (84.081%) and the highest RR in SGF (0.657 ppm/day). Furthermore, liposomes loaded with 10% Cchol and 20% CGA performed best in SIF, while those loaded with 10% Cchol and 30% CGA performed best in SGF. Lastly, the CCL/GA performed better in SIF than SGF.

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